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==Signalment==
 
==Signalment==
 
Young to middle-aged cats, 50% are under 4 years old.
 
Young to middle-aged cats, 50% are under 4 years old.
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===Clinical Signs===
 
===Clinical Signs===
 
*History of chronic waxing and waning low-grade illness.
 
*History of chronic waxing and waning low-grade illness.
*Vague clinical signs which may include  
+
Vague clinical signs which may include anorexia, depression, weight loss, intermittent [[Stomach and Abomasum Consequences of Gastric Disease - Pathology|vomiting]] and [[Diarrhoea|diarrhoea]], [[Icterus|jaundice]],lymphadenomegaly. Severe illness and pyrexia is less likely compared to [[Cholangitis, Neutrophilic]].   
**anorexia
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Some cats in the UK are polyphagic and are frequently presented with ascites and/or jaundice.
**depression
  −
**weight loss
  −
**intermittent [[Stomach and Abomasum Consequences of Gastric Disease - Pathology|vomiting]] and [[Diarrhoea|diarrhoea]]
  −
**[[Icterus|jaundice]]
  −
**lymphadenomegaly
  −
*Severe illness and pyrexia is less likely compared to [[Cholangitis, Neutrophilic]].   
  −
*Some cats in the UK are polyphagic and are frequently presented with ascites and/or jaundice.
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===Histopathology===
 
===Histopathology===
Liver biopsy is important to rule out Feline Infectious Peritonitis.  It is vital to obtain a haemostasis profile prior to biopsy due to risk of prolonged coagulation with liver disease.  It is unnecessary to obtain a bile sample unless the presentation is acute, in which case [[Cholangitis, Neutrophilic]] needs to be ruled out.
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Liver biopsy is important to rule out [[Feline Infectious Peritonitis]]|Feline Infectious Peritonitis]] .  It is vital to obtain a haemostasis profile prior to biopsy due to risk of prolonged coagulation with liver disease.  It is unnecessary to obtain a bile sample unless the presentation is acute, in which case [[Cholangitis, Neutrophilic]] needs to be ruled out.
     
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