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Cholestasis, Molecular Pathogenesis (view source)
Revision as of 20:46, 28 June 2010
, 20:46, 28 June 2010no edit summary
*cAMP mediated signaling in the hepatocyte is impaired due changes in G protein expression and localization. This together with changes in membrane composition and the detergent effects of the bile salts – contribute to decreased adenylate cyclase activity. Also therefore decrease effects of glucagons and VIP that normal stimulate bile secretion.
*cAMP mediated signaling in the hepatocyte is impaired due changes in G protein expression and localization. This together with changes in membrane composition and the detergent effects of the bile salts – contribute to decreased adenylate cyclase activity. Also therefore decrease effects of glucagons and VIP that normal stimulate bile secretion.
[[Category:Liver_-_General_Pathology]]
[[Category:Liver_-_General_Pathology]]
[[Category:To_Do_-_Clinical]]