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Text replace - 'Intestine Diarrhoea - Pathology' to 'Diarrhoea'
* The enteritis caused by colibacillosis is relatively mild although the [[Intestine Diarrhoea - Pathology|diarrhoea]] can be severe.
* The enteritis caused by colibacillosis is relatively mild although the [[Diarrhoea|diarrhoea]] can be severe.
* Only a few strains of coliform organisms cause disease.
* Only a few strains of coliform organisms cause disease.
** These are identified by their serotypes.
** These are identified by their serotypes.
====Pathogenesis====
====Pathogenesis====
* There are three mechanisms by which coliform organisms cause [[Intestine Diarrhoea - Pathology|diarrhoea]].
* There are three mechanisms by which coliform organisms cause [[Diarrhoea|diarrhoea]].
=====Enterotoxigenic [[Escherichia coli|''E. Coli'']] (ETEC)=====
=====Enterotoxigenic [[Escherichia coli|''E. Coli'']] (ETEC)=====
* Cause neonatal and post-weaning [[Intestine Diarrhoea - Pathology|diarrhoea]] in ruminants and pigs.
* Cause neonatal and post-weaning [[Diarrhoea|diarrhoea]] in ruminants and pigs.
** In calves, ETEC are only seen in animals of 4-5 days, or possibly up to one week, of age.
** In calves, ETEC are only seen in animals of 4-5 days, or possibly up to one week, of age.
*** If the animal is older than 1 week, the agent is NOT ETEC.
*** If the animal is older than 1 week, the agent is NOT ETEC.
* Bacteria adhere to enterocyte receptors using pili e.g. K87 (Especially in pigs), K88, K99 (especialoly in cattle).
* Bacteria adhere to enterocyte receptors using pili e.g. K87 (Especially in pigs), K88, K99 (especialoly in cattle).
** Toxins produced by the bacteria encourage loss of Cl<sup>-</sup>, Na<sup>+</sup> and water in gut secretions.
** Toxins produced by the bacteria encourage loss of Cl<sup>-</sup>, Na<sup>+</sup> and water in gut secretions.
*** Causes [[Intestine Diarrhoea - Pathology|diarrhoea]] and dehydration.
*** Causes [[Diarrhoea|diarrhoea]] and dehydration.
*** Death is a result of dehydration and electrolyte loss.
*** Death is a result of dehydration and electrolyte loss.
* To be pathogenic, ETECs require 2 qualities not found in non-pathogenic coliform organisms.
* To be pathogenic, ETECs require 2 qualities not found in non-pathogenic coliform organisms.