Difference between revisions of "Corpus Luteum Regression - Anatomy & Physiology"
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<big><center>[[Female Reproductive Tract -The Ovary - Anatomy & Physiology|'''BACK TO THE OVARY''']]</center></big> | <big><center>[[Female Reproductive Tract -The Ovary - Anatomy & Physiology|'''BACK TO THE OVARY''']]</center></big> | ||
<big><center>[[Female_Reproductive_Tract_-The_Ovary_-_Anatomy_%26_Physiology#Processes_Taking_Place_In_The_Ovary|'''BACK TO PROCESSES TAKING PLACE IN THE OVARY''']]</center></big> | <big><center>[[Female_Reproductive_Tract_-The_Ovary_-_Anatomy_%26_Physiology#Processes_Taking_Place_In_The_Ovary|'''BACK TO PROCESSES TAKING PLACE IN THE OVARY''']]</center></big> | ||
| + | |||
| + | * Prostaglandin F2 (PGF2) | ||
| + | * PGF2 from the uterus is transported to the ipsilateral ovary through a vascular counter-current exchange mechanism. | ||
| + | * This involves two closely associated blood vessels in which blood from one vessel flows in the opposite direction to that of the adjacent vessel. | ||
| + | * Low molecular weight substances in high concentrations in one vessel cross over into the adjacent vessel, where they are low in concentration. | ||
| + | * The ovarian artery lies in closs association with the utero-ovarian vein. | ||
| + | * By counter-current exchange, PGF2 is transferred across the wall of the uterine vein into the ovarian artery by passive diffusion. | ||
| + | * This ensures a high proportion of PGF2 produced by the uterine glands will be transported directly to the ovary and corpus luteum without dilution in the systemic circulation. | ||
| + | * This is an important mechanism, because much PGF2 is denatured during one pass through the circulatory system. This is about a 90% loss in the ewe and cow. | ||
Revision as of 21:11, 12 September 2008
- Prostaglandin F2 (PGF2)
- PGF2 from the uterus is transported to the ipsilateral ovary through a vascular counter-current exchange mechanism.
- This involves two closely associated blood vessels in which blood from one vessel flows in the opposite direction to that of the adjacent vessel.
- Low molecular weight substances in high concentrations in one vessel cross over into the adjacent vessel, where they are low in concentration.
- The ovarian artery lies in closs association with the utero-ovarian vein.
- By counter-current exchange, PGF2 is transferred across the wall of the uterine vein into the ovarian artery by passive diffusion.
- This ensures a high proportion of PGF2 produced by the uterine glands will be transported directly to the ovary and corpus luteum without dilution in the systemic circulation.
- This is an important mechanism, because much PGF2 is denatured during one pass through the circulatory system. This is about a 90% loss in the ewe and cow.