Changes

Creatine Kinase (CK) is considered to be derived predominantly from skeletal muscle and is useful in conjunction with nonspecific tests for hepatobiliary function (AST) to rule out coexistent skeletal muscle injury.

Creatine Kinase (CK) is considered to be derived predominantly from skeletal muscle and is useful in conjunction with nonspecific tests for hepatobiliary function (AST) to rule out coexistent skeletal muscle injury.

== CK (Creatine Kinase) ==

==CK (Creatine Kinase) ==

Formerly known as creatine phosphokinase (CPK). CK occurs in high levels in skeletal muscle, cardiac muscle and brain tissue although only skeletal and cardiac muscle isoenzymes are of major significance. CK is essential for the rapid conversion of ADP to ATP which releases energy for muscle contraction. If muscle tissue is disrupted, the enzyme is released into the blood stream and is readily detected. CK is a highly sensitive indicator of muscle damage but is poorly specific for any particular disease. Levels are frequently elevated when there is muscle damage secondary to other disease, for example collapsed/recumbent animals, seizure activity. CK increases are observed in anorexic cats.

Formerly known as creatine phosphokinase (CPK). CK occurs in high levels in skeletal muscle, cardiac muscle and brain tissue although only skeletal and cardiac muscle isoenzymes are of major significance. CK is essential for the rapid conversion of ADP to ATP which releases energy for muscle contraction. If muscle tissue is disrupted, the enzyme is released into the blood stream and is readily detected. CK is a highly sensitive indicator of muscle damage but is poorly specific for any particular disease. Levels are frequently elevated when there is muscle damage secondary to other disease, for example collapsed/recumbent animals, seizure activity. CK increases are observed in anorexic cats.

Causes of increased CK activity

Causes of increased CK activity

* Trauma (surgery, i/m injections, complicated venipuncture, recumbency, severe exertion and cramping in greyhounds)  

*Trauma (surgery, i/m injections, complicated venipuncture, recumbency, severe exertion and cramping in greyhounds)

* Seizures

*Seizures

* Hypothyroidism

*Hypothyroidism

* Myositis (infectious, immune-mediated, nutritional)

*Myositis (infectious, immune-mediated, nutritional)

Complementary tests

Complementary tests

Causes of increased CK activity

Causes of increased CK activity

* Muscle damage for example, exertional rhabdomyolysis n Trauma (i/m injections, surgery, severe exertion)

*Muscle damage for example, exertional rhabdomyolysis n Trauma (i/m injections, surgery, severe exertion)

* After endurance rides

* After endurance rides

* Nutritional myodegeneration

*Nutritional myodegeneration

* Malignant hyperthermia

*Malignant hyperthermia

Rare causes of increased CK activity  

Rare causes of increased CK activity  

* Myocardial infarction

*Myocardial infarction

* Hypothyroidism

*Hypothyroidism

* Post anaesthetic myopathy

* Post anaesthetic myopathy

Please visit [https://www.nwlabs.co.uk/ www.nwlabs.co.uk] or see our current price list for more information  

Please visit [https://www.nwlabs.co.uk/ www.nwlabs.co.uk] or see our current price list for more information  

[[Category:Lizard_and_Snake_Glossary]]

[[Category:Lizard and Snake Glossary]]