WikiDrugsWikiDrugs Banner.png
WIKIDRUGS
GASTROINTESTINAL DRUGS


Drugs Increasing Smooth Muscle Contractility

These drugs are used for conditions that are associated with hypomotility, such as megacolon, oesophageal reflux, atony and ileus.

Drugs Acting on 5-HT4 Receptors

  • An examples is metoclopramide that is an agonist at serotonin and dopamine receptors, this results in an increased release of acetylcholine and so increases gut motility.

Muscarinic Receptor Agonists

  • Examples are carbachol and bethanecol. They should be used with slight caution as their resultant contractions can be painful.

Laxatives and Purgatives

Drugs Decreasing Smooth Muscle Contractility

Other Drugs