EPI

BACK TO PANCREAS - DEVELOPMENTAL

• Exocrine pancreatic insufficiency (EPI) is a syndrome caused by insufficient synthesis and secretion of digestive enzymes by the exocrine portion of the pancreas
• Leading to insufficient activity of digestive enzymes in the lumen of the small intestine
• Pancreas has considerable functional reserve, large proportion needs to be non-functional to show signs of EPI
• Most common in dog - usually associated with pancreatic atrophy or chronic pancreatitis