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There are various hormones that may infulence the structure of the skin.  These influences may be made apparent by the repeated long-term administration of various glucocorticoids or their analogues.  Endogenous imbalances are generally seen in adult mature animals although congenital forms have been seen, especially with [[Endocrine System - Thyroid Gland - Anatomy & Physiology#Problems associated with the Thyroid Gland|hypothyroidism]].  The hormones implicated as important for maintaining skin structure are '''thyroxine, cortisol''' and '''estradiol'''.  Deficiencies or excessive production may result from abberations in the function of the [[Endocrine System - Adrenal Glands - Anatomy & Physiology|hypothalamic-adrenal axis]],  the '''adrenal gland, thyroid gland''' and the '''gonads'''.
 
There are various hormones that may infulence the structure of the skin.  These influences may be made apparent by the repeated long-term administration of various glucocorticoids or their analogues.  Endogenous imbalances are generally seen in adult mature animals although congenital forms have been seen, especially with [[Endocrine System - Thyroid Gland - Anatomy & Physiology#Problems associated with the Thyroid Gland|hypothyroidism]].  The hormones implicated as important for maintaining skin structure are '''thyroxine, cortisol''' and '''estradiol'''.  Deficiencies or excessive production may result from abberations in the function of the [[Endocrine System - Adrenal Glands - Anatomy & Physiology|hypothalamic-adrenal axis]],  the '''adrenal gland, thyroid gland''' and the '''gonads'''.
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Cutaneous changes may include [[Anatomy & Physiology of the Hair#Hair Types|telogen]] hair follicles leading to [[Skin - glossary|alopecia]], epidermal and dermal thinning, atrophy of [[Anatomy & Physiology of the Skin#Glands|sebaceous glands]] and the [[Anatomy & Physiology of the Hair|arrector pili]] muscles.  There may also be an increased risk of microbial infection due to poor immune surveillance and delayed wound healing.  There are significant differences between species in the manifestation of symptoms.
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Cutaneous changes may include [[Anatomy & Physiology of the Hair#Hair Types|telogen]] hair follicles leading to [[Skin Glossary - Pathology|alopecia]], epidermal and dermal thinning, atrophy of [[Anatomy & Physiology of the Skin#Glands|sebaceous glands]] and the [[Anatomy & Physiology of the Hair|arrector pili]] muscles.  There may also be an increased risk of microbial infection due to poor immune surveillance and delayed wound healing.  There are significant differences between species in the manifestation of symptoms.
    
==Nutrition and the Skin==
 
==Nutrition and the Skin==
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Trace elements such as '''copper''' are rarely deficient in farm animals, although deficiency can be associated with poor fertility, ill-thrift and leukotrichia - leading to perioccular 'spectacles'.  This reflects the role of copper in the formation of [[Skin - Anatomy & Physiology#Cells of the Epidermis|melanin]].
 
Trace elements such as '''copper''' are rarely deficient in farm animals, although deficiency can be associated with poor fertility, ill-thrift and leukotrichia - leading to perioccular 'spectacles'.  This reflects the role of copper in the formation of [[Skin - Anatomy & Physiology#Cells of the Epidermis|melanin]].
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Excessive exposure to trace elements can also have harmful effects and again, although rare, examples may include '''selenosis''' which is usually seen as [[Skin - glossary|alopecia]] in geographical areas with high '''selenium''' soil content for grazing animals.
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Excessive exposure to trace elements can also have harmful effects and again, although rare, examples may include '''selenosis''' which is usually seen as [[Skin Glossary - Pathology|alopecia]] in geographical areas with high '''selenium''' soil content for grazing animals.
    
===Vitamins===
 
===Vitamins===

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