Changes

Jump to navigation Jump to search
Line 57: Line 57:     
In early disease, lymphadenopathy is seen histologically to be due to follicular hyperplasia and infiltration of plasmacytes to surround the cortex. Later in disese, a mixutre of follicular hyperplasia and follicular depletion may exist, and in the terminal stages of FIV infection, follicular involution is the key feature<sup>5</sup>. Lymphoplasmacytic infiltrates are seen in the gingiva, lymphoid tissues, spleen, kidney, liver and brain. Brain lesions also include perivascular cuffing, gliosis, neuronal loss, vacuolation of the white matter and, occasionally, the presence of giant cells.
 
In early disease, lymphadenopathy is seen histologically to be due to follicular hyperplasia and infiltration of plasmacytes to surround the cortex. Later in disese, a mixutre of follicular hyperplasia and follicular depletion may exist, and in the terminal stages of FIV infection, follicular involution is the key feature<sup>5</sup>. Lymphoplasmacytic infiltrates are seen in the gingiva, lymphoid tissues, spleen, kidney, liver and brain. Brain lesions also include perivascular cuffing, gliosis, neuronal loss, vacuolation of the white matter and, occasionally, the presence of giant cells.
  −
==Prognosis==
  −
  −
The long-term prognosis for FIV-infected cats is guarded, but some cats will survive for many years following diagnosis. A cat should therefore never be euthanased based on a positive test result for FIV,sup>4</sup>. Around 20% of affected cats die within the first two years after diagnosis; this equates to a 20% mortality rate in the first 4.5-6 years after the estimated time of infection<sup>fmc</sup>. In generally, the more chronic and severe the clinical signs, the worse the prognosis is. The duration of the asymptomatic period following FIV infection varies with the infecting strain and cannot be predicted. However, cats affected at a younger age are more likely to progress to an immunodeficient state<sup>4</sup>.
      
==Treatment==
 
==Treatment==
6,502

edits

Navigation menu