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{{Template:Manson Sparkes}}
 
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This cat is showing ventroflexion of the neck, a classic sign of neuromuscular weakness.
 
This cat is showing ventroflexion of the neck, a classic sign of neuromuscular weakness.
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|l1=Neurological Examination - Dog & Cat#Posture
 
|q2=What differential diagnoses should be considered?
 
|q2=What differential diagnoses should be considered?
 
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*Junctionopathies: myasthenia gravis (congenital, acquired, paraneoplastic), organophosphate intoxication.
 
*Junctionopathies: myasthenia gravis (congenital, acquired, paraneoplastic), organophosphate intoxication.
 
Hypokalaemia is probably the single most common cause of this type of presentation.
 
Hypokalaemia is probably the single most common cause of this type of presentation.
In this cat, the accompanying clinical signs (polydipsia, polyuria, weight loss, and intermittent vomiting) would be strongly suggestive of hypokalaemia secondary to CRF. However, hyperthyroidism would also be an important differential, as would
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In this cat, the accompanying clinical signs (polydipsia, polyuria, weight loss, and intermittent vomiting) would be strongly suggestive of hypokalaemia secondary to CRF.  
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However, hyperthyroidism would also be an important differential, as would
 
paraneoplastic disease (e.g. with hypercalcaemia causing polyuria and polydipsia).
 
paraneoplastic disease (e.g. with hypercalcaemia causing polyuria and polydipsia).
|l2=Chronic Renal Failure
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|l2=Hypokalaemia
 
|q3=What are the priorities for further investigation?
 
|q3=What are the priorities for further investigation?
 
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Priorities for further investigation would be a thorough history, physical and neurological examination. A neurological examination should aim to detect any specific deficits, and distinguish muscle weakness from neurological disease (e.g. by careful assessment of proprioceptive responses). Initial screening blood tests should include serum biochemistry (including CK, urea, creatinine, calcium, phosphate, sodium, potassium, thyroxine) and urinalysis.
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Priorities for further investigation would be a thorough history, physical and neurological examination.  
|l3=Chronic Renal Failure
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A neurological examination should aim to detect any specific deficits, and distinguish muscle weakness from neurological disease (e.g. by careful assessment of proprioceptive responses).  
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Initial screening blood tests should include serum biochemistry (including CK, urea, creatinine, calcium, phosphate, sodium, potassium, thyroxine) and urinalysis.
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|l3=Neurological Examination - Dog & Cat#Further Investigation
 
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