Changes

===Clinical Signs===

===Clinical Signs===

Certain elements of a patient's history may be suggestive of feline panleucopenia. For example, the animal may have recently been exposed to a potential source of infection, such as a cattery, or be a kitten obtained from a premisis with a history of feline panleucopenia. Lack of vaccination, or vaccination before the demise of maternally-derived antibodies, may also point to FPV infection. Owners usually report a sudden onset of illness including vomiting, diarrhoea, depression and complete anorexia, and cats are often said to hang their head over the food or water bowl but do not actually eat or drink.

Certain elements of a patient's history may be suggestive of feline panleucopenia. For example, the animal may have recently been exposed to a potential source of infection, such as a cattery, or be a kitten obtained from a premisis with a history of feline panleucopenia. Lack of vaccination, or vaccination before the demise of maternally-derived antibodies, may also point to FPV infection. Owners usually report a sudden onset of illness including vomiting, diarrhoea, depression and complete anorexia, and cats are often said to hang their head over the food or water bowl but do not actually eat or drink.

On clinical examination, cats show varying degrees of depresssion and are often severely dehydrated. Vomiting and diarrhoea may be apparent and body temperature can be mildly to moderately elevated or depressed in the early stages of disease. When the cat becomes severely ill, a markedly subnormal temperature is seen. Some cats are painful on abdominal palpation, and the small intestine can be felt to be either abnormally flaccid or turgid. It is, however, important to remember that subclinical or mild infections are common, especially in adult cats.

On clinical examination, cats show varying degrees of depresssion and are often severely dehydrated. Vomiting and diarrhoea may be apparent and body temperature can be mildly to moderately elevated or depressed in the early stages of disease. When the cat becomes severely ill, a markedly subnormal temperature is seen. Animals are often painful on abdominal palpation, and the small intestine can be felt to be either abnormally flaccid or turgid due to fluid or gas filling. A typical "hunched up" posture is adopted by affected kittens. Damage to the enteric mucosal integrity can lead to secondary infections and sepsis and perforation of the gut can cause peritonitis.  

Infection of the pregnant queen can result in ''in utero'' infection of kittens. This can lead to foetal death, resorbtion, abortion, mummification and stillbirths. Some kittens infected ''in utero'' and those contracting the virus early in neonatal life develop cerebellar hypoplasia which becomes apparent at around 10-14 days old. Affected kittens are ataxic with a wide-based stance, hyper- or dys-metria and a raised tail. Apart from occasional retinal dysplasia, these cats are otherwise normal and healthy and are said to make good pets.

Infection of the pregnant queen may result in ''in utero'' infection of kittens. When this occurs in early to mid gestation, foetal death, resorbtion, abortion or mummification can occur. Infection of kittens in late gestation or early in neonatal life may give cerebellar hypoplasia. This becomes apparent at around 10-14 days old. Affected kittens are ataxic with a wide-based stance, inco-ordination and tremors, and these signs persist for life. Apart from occasional retinal dysplasia, these cats are otherwise normal and healthy and are said to make good pets.

===Radiography===

===Radiography===