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Gross lesions regarding ear mites will include large amounts of a thick black-brown wax. Swabs should be examined microscopically for the presence of adult mites and/or their eggs. Gross lesions relating to sarcoptic mange are characterised by swollen feet, evidence of self-mutilation and nail loss. Microscopically, mange lesions will include marked ulceration and hyperkeratosis of the skin. There may also be some cross sections of mites in the epidermis or deep under the overlying crust. Skin scrapings may microscopically demonstrate demodectic mange via the presence of nymphs or adults. Skin biopsies should reveal moderate hyperkeratosis and the presence of mites (cigar shaped) within the hair follicles.
 
Gross lesions regarding ear mites will include large amounts of a thick black-brown wax. Swabs should be examined microscopically for the presence of adult mites and/or their eggs. Gross lesions relating to sarcoptic mange are characterised by swollen feet, evidence of self-mutilation and nail loss. Microscopically, mange lesions will include marked ulceration and hyperkeratosis of the skin. There may also be some cross sections of mites in the epidermis or deep under the overlying crust. Skin scrapings may microscopically demonstrate demodectic mange via the presence of nymphs or adults. Skin biopsies should reveal moderate hyperkeratosis and the presence of mites (cigar shaped) within the hair follicles.
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'''Pemphigus foliaceous'''
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This disease in ferrets has similar symptoms to those in other species.
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Gross lesions include generalised eruptions and vesicular lesions. These lesions are most commonly intracorneal pustules containing rafts of acantholytic (loss of cohesion), a thickened epidermis and prominent superficial lymphocytic and eosinophilic dermatitis.
 
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