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| + | [[Image:Fertilization histology.jpg|right|thumb|250px|<small><center> Electron Scanning Micrograph of Spermatozoa in the Uterine Horn. Copyright RVC 2008 (Courtesy of John Bredl (RVC))</center></small>]] |
− | |backcolour =EED2EE | + | |
− | |linkpage =Reproductive System - Anatomy & Physiology | |
− | |linktext =Reproductive System | |
− | |maplink = Reproductive System (Content Map) - Anatomy & Physiology | |
− | |pagetype =Anatomy
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− | |sublink1=Reproductive System - Anatomy & Physiology#Fertilisation.2C Implantation and Early Embryonic Development
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− | |subtext1=FERTILISATION , IMPLANTATION AND EARLY EMBRYONIC DEVELOPMENT'''
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| == Fusion with the Oocyte == | | == Fusion with the Oocyte == |
− | * When the spermatozoan completely penetrates the zona pellucida and reaches the perivitelline space, it settles into a bed of '''microvilli''' formed by the oocyte plasma membrane. | + | * When the spermatozoon completely penetrates the zona pellucida and reaches the perivitelline space, it settles into a bed of '''microvilli''' formed by the oocyte plasma membrane. |
| * Oocyte plasma membrane fuses with the '''equitorial segment''' and the fertilizing spermatozoon is engulfed. | | * Oocyte plasma membrane fuses with the '''equitorial segment''' and the fertilizing spermatozoon is engulfed. |
− | **Brought about by a fusion protein that is inactive prior to the [[Copulation_-Sperm_in_the_Female_Tract_-_Anatomy_%26_Physiology|acrosome reaction]]. | + | **Brought about by a fusion protein that is inactive prior to the [[Sperm in the Female Tract - Anatomy & Physiology|acrosome reaction]]. |
| * Nucleus of the spermatozoon is within the oocyte cytoplasm. | | * Nucleus of the spermatozoon is within the oocyte cytoplasm. |
| * Sperm nuclear membrane disappears. | | * Sperm nuclear membrane disappears. |
| * Sperm '''nucleus decondenses'''. | | * Sperm '''nucleus decondenses'''. |
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− | [[Image:Fertilization histology.jpg|right|thumb|250px|<small><center> Electron Scanning Micrograph of Spermatozoa in the Uterine Horn. Copyright RVC 2008 (Courtesy of John Bredl (RVC))</center></small>]]
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| == Cortical Reaction - Block to Polyspermy == | | == Cortical Reaction - Block to Polyspermy == |
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| ''N.B: Although sperm mitochondria enters the Ooctye cytoplasm, they carry a ubiquitin signal. They are subsequently destroyed by Ubiquiitinase and do NOT contribute to mitochondrial DNA. Therefore mitochondial DNA is entirely from the maternal side.'' | | ''N.B: Although sperm mitochondria enters the Ooctye cytoplasm, they carry a ubiquitin signal. They are subsequently destroyed by Ubiquiitinase and do NOT contribute to mitochondrial DNA. Therefore mitochondial DNA is entirely from the maternal side.'' |
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| + | [[Category:Pregnancy and Parturition]] |
| + | [[Category:Bullet Points]] |