Changes

===Other ailments===

===Other ailments===

The association between intestinal lesions and ulcers within the stomach might suggest that gastric ulcers are often part of a larger gastrointestinal disease complex.  Murray (1989) reported an association between glandular ulcers and clinical disorders in foals and a similar relationship could also be true for mature horses. It has also been established that colic is associated with gastric ulcers in horses (Murray 1989, 1992; Furr and Murray 1989). A variety of conditions involving abdominal pain (Murray

1992) have also been associated with gastric ulceration in horses. Abdominal pain or inappetance for any reason probably reduces appetite and, consequently, diminishes feed intake. Therefore, any condition that considerably influences food intake might, hypothetically, contribute to the development of gastric ulcers in horses.(Sandin 2000)

Conditions that produce abdominal pain or inappetance are likely to reduce food intake and predipose to gastric ulcers (Sandin 2000).  This may be the reason that colic and other gastrointestinal disorders have been associated with EGUS (Murray 1989, 1992; Furr and Murray 1989(Murray 1992). Alternatively, EGUS may be part of a more general gastrointestinal disease complex.(Vatistas 2 1999) Stress induced by other clinical disorders has been reported to increase the prevalence of EGUS in neonatal foals (Furr et al. 1992) and a similar mechanism may exist for adult animals.(Vatistas 2 1999)

Stress, due to concurrent disease, has been documented to increase the prevalence of peptic ulcer disease in neonatal foals (Furr et al. 1992).(Vatistas 2 1999)

===NSAIDs===

===NSAIDs===