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====Diet====
====Diet====
'''Feed deprivation''' encourages gastric ulceration in two ways: (1) it precludes the buffering capacity of protein leading to a reduced gastric pH<ref>Murray, M.J, Schusser, G.F (1993) Measurement of 24-h gastric pH using an indwelling pH electrode in horses unfed, fed and treated with ranitidine. ''Equine Vet J'', 25:417-421. In: Sandin, A, Skidell, J, Haggstrom, J, Nilsson, G (2000) ''Postmortem'' findings of gastric ulcers in Swedish horses older than age one year: a retrospective study of 3715 horses (1924–1996). ''Equine Vet J'', 32(1):36-42.</ref> and (2) it empties the stomach and exposes the squamous mucosa to the more mobile gastric juice.<ref name="Sandin">Sandin, A, Skidell, J, Haggstrom, J, Nilsson, G (2000) ''Postmortem'' findings of gastric ulcers in Swedish horses older than age one year: a retrospective study of 3715 horses (1924–1996). ''Equine Vet J'', 32(1):36-42.</ref> It is unsurprising, therefore, that an alternating feed-fast protocol would produce a consistent model of ulcer induction in the equine squamous mucosa.<ref>Murray, M.J, Schusser, G.F (1993) Measurement of 24-h gastric pH using an indwelling pH electrode in horses unfed, fed and treated with ranitidine. ''Equine Vet J'', 25:417-421. In: Sanchez, L.C (2010) 'Diseases Of The Stomach' in Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) '''Equine Internal Medicine''' (Third Edition), Saunders, Chapter 15.</ref><ref>Murray, M.J (1994) Equine model of inducing ulceration in alimentary squamous epithelial mucosa. ''Dig Dis Sci'', 39:2530-2535. In: Sanchez, L.C (2010) 'Diseases Of The Stomach' in Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) '''Equine Internal Medicine''' (Third Edition), Saunders, Chapter 15.</ref> Despite this, feed deprivation is not a prerequisite for gastric ulceration in the horse.<ref name="Vatistas thesis">Vatistas, N.J (1998) Gastric Ulceration in the Racing Thoroughbred. ''PhD Thesis''. In: Vatistas, N.J, Sifferman, R.L, Holste, J, Cox, J.L, Pinalto, G, Schultz, K.T (1999) Induction and maintenance of gastric ulceration in horses in simulated race training. ''Equine Vet J Suppl'', 29:40-44</ref> Diets that are plentiful in roughage prolong the mastication process and the production of salivary bicarbonate that protects the gastric mucosa. A diet of '''high grain and low roughage''' thus predisposes to EGUS.<ref name="Nadeau"> In: Nadeau, J.A, Andrews, F.M (2009) ''Science: Overviews'' Equine gastric ulcer syndrome: The continuing conundrum. ''Equine Vet J'', 41(7):611-615.</ref> This sort of diet is commonly fed to racehorses but dietary components have also been shown to influence EGUS risk in nonracehorses.<ref>Luthersson, N, Nielson, K.H, Harris, P, Parkin, T.D (2009) Risk factors associated with equine gastric ulceration syndrome (EGUS) in 201 horses in Denmark. ''Equine Vet J'', 41(7):625-30.</ref> Ponies fed a '''concentrate diet''' had a greater prevalence of gastric ulcers than ponies fed hay alone.<ref name="Vatistas 2">Vatistas, N.J, Sifferman, R.L, Holste, J, Cox, J.L, Pinalto, G, Schultz, K.T (1999) Induction and maintenance of gastric ulceration in horses in simulated race training. ''Equine Vet J Suppl'', 29:40-44</ref> and this may be because grain and pelleted feeds are asssociated with increased serum gastrin.<ref>Smyth, G.B, Young, D.W, Hammond, L.S (1988) Effects of diet and feeding on post-prandial serum gastrin and insulin concentrations in adult horses. ''Equine Vet J Suppl'' 7:56-59.</ref> '''High starch meals''' are also a risk because they are fermented to volatile fatty acids (VFAs) and lactic acid and are emptied from the stomach relatively slowly.<ref>Mètayer, N, Lhôte, M, Bahr, A, Cohen, N.D, Kim, I, Rousell, A.J, Julliand, V (2004) Meal size and starch content affect gastric emptying in horses. ''Equine Vet J'', 36:434-440. In: Nadeau, J.A, Andrews, F.M (2009) ''Science: Overviews'' Equine gastric ulcer syndrome: The continuing conundrum. ''Equine Vet J'', 41(7):611-615.</ref><ref>Taharaguchi, S, Okai, K, Orita, Y, Kuwano, M, Ueno, T, Taniyama, H (2004) Relation between amounts of concentrated feed given mares and gastric ulcers in foals. ''J Japan Vet Med Ass'', 57:366-370. In: Nadeau, J.A, Andrews, F.M (2009) ''Science: Overviews'' Equine gastric ulcer syndrome: The continuing conundrum. ''Equine Vet J'', 41(7):611-615.</ref><ref>Boswinkel, A.M, Ellis, A.D, Sloet van Oldruitenborgh-Oosterbaan, M.M (2007) The influence of low versus high fibre haylage diets in combination with training or pasture rest on equine gastric ulceration syndrome (EGUS). ''Pferdeheilkunde'', 23:123-130. In: Nadeau, J.A, Andrews, F.M (2009) ''Science: Overviews'' Equine gastric ulcer syndrome: The continuing conundrum. ''Equine Vet J'', 41(7):611-615.</ref>
'''Feed deprivation''' encourages gastric ulceration in two ways: (1) it precludes the buffering capacity of protein leading to a reduced gastric pH<ref>Murray, M.J, Schusser, G.F (1993) Measurement of 24-h gastric pH using an indwelling pH electrode in horses unfed, fed and treated with ranitidine. ''Equine Vet J'', 25:417-421. In: Sandin, A, Skidell, J, Haggstrom, J, Nilsson, G (2000) ''Postmortem'' findings of gastric ulcers in Swedish horses older than age one year: a retrospective study of 3715 horses (1924–1996). ''Equine Vet J'', 32(1):36-42.</ref> and (2) it empties the stomach and exposes the squamous mucosa to the more mobile gastric juice.<ref name="Sandin">Sandin, A, Skidell, J, Haggstrom, J, Nilsson, G (2000) ''Postmortem'' findings of gastric ulcers in Swedish horses older than age one year: a retrospective study of 3715 horses (1924–1996). ''Equine Vet J'', 32(1):36-42.</ref> It is unsurprising, therefore, that an alternating feed-fast protocol would produce a consistent model of ulcer induction in the equine squamous mucosa.<ref>Murray, M.J, Schusser, G.F (1993) Measurement of 24-h gastric pH using an indwelling pH electrode in horses unfed, fed and treated with ranitidine. ''Equine Vet J'', 25:417-421. In: Sanchez, L.C (2010) 'Diseases Of The Stomach' in Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) '''Equine Internal Medicine''' (Third Edition), Saunders, Chapter 15.</ref><ref>Murray, M.J (1994) Equine model of inducing ulceration in alimentary squamous epithelial mucosa. ''Dig Dis Sci'', 39:2530-2535. In: Sanchez, L.C (2010) 'Diseases Of The Stomach' in Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) '''Equine Internal Medicine''' (Third Edition), Saunders, Chapter 15.</ref> Despite this, feed deprivation is not a prerequisite for gastric ulceration in the horse.<ref name="Vatistas thesis">Vatistas, N.J (1998) Gastric Ulceration in the Racing Thoroughbred. ''PhD Thesis''. In: Vatistas, N.J, Sifferman, R.L, Holste, J, Cox, J.L, Pinalto, G, Schultz, K.T (1999) Induction and maintenance of gastric ulceration in horses in simulated race training. ''Equine Vet J Suppl'', 29:40-44</ref> Diets that are plentiful in roughage prolong the mastication process and the production of salivary bicarbonate that protects the gastric mucosa. A diet of '''high grain and low roughage''' thus predisposes to EGUS.<ref name="Nadeau"> In: Nadeau, J.A, Andrews, F.M (2009) ''Science: Overviews'' Equine gastric ulcer syndrome: The continuing conundrum. ''Equine Vet J'', 41(7):611-615.</ref> This sort of diet is commonly fed to racehorses but dietary components have also been shown to influence EGUS risk in nonracehorses.<ref>Luthersson, N, Nielson, K.H, Harris, P, Parkin, T.D (2009) Risk factors associated with equine gastric ulceration syndrome (EGUS) in 201 horses in Denmark. ''Equine Vet J'', 41(7):625-30.</ref> Ponies fed a '''concentrate diet''' had a greater prevalence of gastric ulcers than ponies fed hay alone.<ref name="Vatistas 2">Vatistas, N.J, Sifferman, R.L, Holste, J, Cox, J.L, Pinalto, G, Schultz, K.T (1999) Induction and maintenance of gastric ulceration in horses in simulated race training. ''Equine Vet J Suppl'', 29:40-44</ref> and this may be because grain and pelleted feeds are asssociated with increased serum gastrin.<ref>Smyth, G.B, Young, D.W, Hammond, L.S (1988) Effects of diet and feeding on post-prandial serum gastrin and insulin concentrations in adult horses. ''Equine Vet J Suppl'' 7:56-59.</ref> '''High starch meals''' are also a risk because they are fermented to volatile fatty acids (VFAs) and lactic acid and are emptied from the stomach relatively slowly.<ref>Mètayer, N, Lhôte, M, Bahr, A, Cohen, N.D, Kim, I, Rousell, A.J, Julliand, V (2004) Meal size and starch content affect gastric emptying in horses. ''Equine Vet J'', 36:434-440. In: Nadeau, J.A, Andrews, F.M (2009) ''Science: Overviews'' Equine gastric ulcer syndrome: The continuing conundrum. ''Equine Vet J'', 41(7):611-615.</ref><ref>Taharaguchi, S, Okai, K, Orita, Y, Kuwano, M, Ueno, T, Taniyama, H (2004) Relation between amounts of concentrated feed given mares and gastric ulcers in foals. ''J Japan Vet Med Ass'', 57:366-370. In: Nadeau, J.A, Andrews, F.M (2009) ''Science: Overviews'' Equine gastric ulcer syndrome: The continuing conundrum. ''Equine Vet J'', 41(7):611-615.</ref><ref>Boswinkel, A.M, Ellis, A.D, Sloet van Oldruitenborgh-Oosterbaan, M.M (2007) The influence of low versus high fibre haylage diets in combination with training or pasture rest on equine gastric ulceration syndrome (EGUS). ''Pferdeheilkunde'', 23:123-130. In: Nadeau, J.A, Andrews, F.M (2009) ''Science: Overviews'' Equine gastric ulcer syndrome: The continuing conundrum. ''Equine Vet J'', 41(7):611-615.</ref>
'''Diet and feeding regime:'''Berschenider, grain vs hay alone and gastric pH, feed deprivation, feed-fast protocol,
====Other ailments====
====Other ailments====