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Also known as: '''''Zollinger-Ellison Syndrome
Also known as: '''''Zollinger-Ellison Syndrome
==Description==
==Introduction==
A gastrinoma is a neoplasm of pancreatic islet cells that secretes the hormone gastrin, an example of an ectopic paraneoplastic disease. The disease was first described by Zollinger and Ellison in humans in 1955 and it has since been recognised occasionally in dogs and cats. Gastrinomas are the least common of the islet cell neoplasia, the other types being [[Glucagonoma|glucagonomas]] and [[Insulinoma|insulinomas]].
A gastrinoma is a neoplasm of pancreatic islet cells that secretes the hormone gastrin, an example of an ectopic paraneoplastic disease. The disease was first described by Zollinger and Ellison in humans in 1955 and it has since been recognised occasionally in dogs and cats. Gastrinomas are the least common of the islet cell neoplasia, the other types being [[Glucagonoma|glucagonomas]] and [[Insulinoma|insulinomas]].
In approximately 85% of cases, gastrinomas have metastasised at the time of diagnosis and the tumour is likely to recur after surgical resection.
In approximately 85% of cases, gastrinomas have metastasised at the time of diagnosis and the tumour is likely to recur after surgical resection.
==Literature Search==
{{Learning
[[File:CABI logo.jpg|left|90px]]
|literature search = [http://www.cabdirect.org/search.html?start=10&q=%28%28title%3A%28%22Zollinger+Ellison%22%29%29%29+OR+%28%28title%3A%28gastrinoma%29%29%29&fq=sc%3A%22ve%22 Gastrinoma publications]
|Vetstream = [https://www.vetstream.com/felis/Content/Disease/dis60205 Gastric neoplasia]
}}
==References==
<references/>
[http://w3.vet.cornell.edu/nst/nst.asp?Fun=Image&imgID=7762 Image of pancreatic gastrinoma in a dog from Cornell Veterinary Medicine]
Ettinger, S.J, Feldman, E.C. (2005) '''Textbook of Veterinary Internal Medicine''' (6th edition, volume 2) ''W.B. Saunders Company''
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[[Category:Pancreas_-_Hyperplastic_and_Neoplastic_Pathology]][[Category:Endocrine_System_-_Pathology]][[Category:Gastric Diseases - Dog]][[Category:Endocrine Diseases - Dog]][[Category:Gastric Diseases - Cat]]
[[Category:Pancreas_-_Hyperplastic_and_Neoplastic_Pathology]][[Category:Endocrine_System_-_Pathology]][[Category:Gastric Diseases - Dog]][[Category:Endocrine Diseases - Dog]][[Category:Gastric Diseases - Cat]]
[[Category:Neoplasia]]
[[Category:Neoplasia]]
[[Category:Expert Review]]
[[Category:Expert Review - Small Animal]]