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| | * Formation of neutrophils, eosinophils and basophils ([[Leukopoiesis#Granulopoiesis|Granulopoiesis]]) | | * Formation of neutrophils, eosinophils and basophils ([[Leukopoiesis#Granulopoiesis|Granulopoiesis]]) |
| | * Formation of B cells and T cells ([[Leukopoiesis#Lymphopoiesis|Lymphopoiesis]]) | | * Formation of B cells and T cells ([[Leukopoiesis#Lymphopoiesis|Lymphopoiesis]]) |
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| − | == Hematopoyesis and Distribution of Cells in the Body ==
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| − | Erythrocytes, platelets and granulocytes (neutrophils, eosinophils and basophils) are derived from pluripotential stem cells. These give rise to multipotential colony-forming unit progenitors for granulocytes, erythrocytes, monocytes/macrophages and megakaryocytes. Under the influence of interleukins and colony-stimulating factors, committed stem cells develop into differentiated blood cells (erythrocytes, neutrophils, eosinophils, basophils, monocytes and platelets). Neutrophils and monocytes develop from the same colony-forming unit. Although the bone marrow produces some lymphocytes most are derived from the peripheral lymphoid tissue.
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| − | The bone marrow also contains a reserve of mature cells, which can be released into the circulation. Thus, changes in the blood are affected by the reserve capacity of the bone marrow and the life span of cells in the circulation (canine erythrocytes 120 days, platelets 10 days, granulocytes 8 hours).
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| − | Haematopoiesis may occur in other organs particularly the spleen, less frequently the liver and even peripheral lymph nodes, if there is a marked increase in demand for cells. With increased tissue demands, mature reserves are depleted and immature cells are released into the circulation.
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| − | References: [[NationWide Laboratories]]
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| − | [[File:NWL 2016 Labfacts inners A4 PRESS optimize(40).jpg|thumb|Bone Marrow Citology and Histology ©NationWide Laboratories 2017]]
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| | [[File:NWL 2016 Labfacts inners A4 PRESS optimize(90).jpg|thumb|Bone Marrow Histology|link=Special:FilePath/NWL_2016_Labfacts_inners_A4_PRESS_optimize(90).jpg]] | | [[File:NWL 2016 Labfacts inners A4 PRESS optimize(90).jpg|thumb|Bone Marrow Histology|link=Special:FilePath/NWL_2016_Labfacts_inners_A4_PRESS_optimize(90).jpg]] |
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| | [http://www.cabi.org/cabdirect/FullTextPDF/2010/20103272114.pdf ''' Role of hematopoitic stem cells in liver injury.''' Jahan, M. S.; Hind Agri-Horticultural Society, Muzaffarnagar, India, Asian Journal of Bio Science, 2010, 5, 1, pp 145-146, 6 ref. - '''Full Text Article'''] | | [http://www.cabi.org/cabdirect/FullTextPDF/2010/20103272114.pdf ''' Role of hematopoitic stem cells in liver injury.''' Jahan, M. S.; Hind Agri-Horticultural Society, Muzaffarnagar, India, Asian Journal of Bio Science, 2010, 5, 1, pp 145-146, 6 ref. - '''Full Text Article'''] |
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| − | Hematopoyesis and Distribution of Cells in the Body: [[NationWide Laboratories]]
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| | [[Category:Haematopoiesis|A]] | | [[Category:Haematopoiesis|A]] |