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| * Foetal ovaries produce oestradiol, but this does NOT defeminize the [[Hypothalamus_-_Anatomy_%26_Physiologyhypothalamus]]. | | * Foetal ovaries produce oestradiol, but this does NOT defeminize the [[Hypothalamus_-_Anatomy_%26_Physiologyhypothalamus]]. |
− | * A protein called alpha-fetoprotein binds oestradiol to prevent it from crossing the blood brain barrier, therefore oestradiol cannot effect the [[hHypothalamus_-_Anatomy_%26_Physiologyypothalamus]]. | + | * A protein called alpha-fetoprotein binds oestradiol to prevent it from crossing the blood brain barrier, therefore oestradiol cannot effect the [[Hypothalamus_-_Anatomy_%26_Physiology|Hypothalamus]]. |
| * Alpha-fetoprotein is synthesized firstly by the embryonic yolk sac and then by the foetal liver. | | * Alpha-fetoprotein is synthesized firstly by the embryonic yolk sac and then by the foetal liver. |
| * Alpha fetoprotein functions as: | | * Alpha fetoprotein functions as: |
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| ** Carrier of fatty acids | | ** Carrier of fatty acids |
| * As GnRH surges, LH and Oestradiol surge ~ every 20 days in the female. | | * As GnRH surges, LH and Oestradiol surge ~ every 20 days in the female. |
− | ** Surge frequency varies between species, dependent on the length of their oestrous cycles. | + | ** Surge frequency varies between species, dependent on the length of their [[Female_Reproductive_Tract_-Oestrous_Cycle_-_Anatomy_%26_Physiology|oestrous cycles]]. |
| * Between surges, there are low amplitude LH pulses. | | * Between surges, there are low amplitude LH pulses. |