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Immunodeficiencies - WikiBlood (view source)
Revision as of 10:30, 14 August 2009
, 10:30, 14 August 2009→Equine Severe Combined Immune Deficiency (Equine SCID)
**Gene codes for a DNA repair enzyme involved in V(D)J recombination for antigen receptors of [[Lymphocytes - WikiBlood|lymphocytes]] (e.g. Ig and TCR)
**Gene codes for a DNA repair enzyme involved in V(D)J recombination for antigen receptors of [[Lymphocytes - WikiBlood|lymphocytes]] (e.g. Ig and TCR)
*No functional [[Lymphocytes - WikiBlood#B cells|B cells]] or [[Lymphocytes - WikiBlood#T cells|T cells]]
*No functional [[Lymphocytes - WikiBlood#B cells|B cells]] or [[Lymphocytes - WikiBlood#T cells|T cells]]
*Foals develop infections (usually aorund 8 weeks of age as maternal [[Immunoglobulins - WikiBlood|antibody]] in [[Materno-fetal immunity - WikiBlood#Passive transfer via colostrum|colostrum]] wanes around this time)
*Foals develop infections (usually around 8 weeks of age as maternal [[Immunoglobulins - WikiBlood|antibody]] in [[Materno-fetal immunity - WikiBlood#Passive transfer via colostrum|colostrum]] wanes around this time)
*Foals usually die from bronchopneumonia
*Foals usually die from bronchopneumonia