Changes

[[Image:LH IgD.png|thumb|250px|right|'''IgD''']]

[[Image:LH IgD.png|thumb|250px|right|'''IgD''']]

[[Image:IgD.jpg|thumb|right|250px|IgD - B. Catchpole, RVC 2008]]

[[Image:IgD.jpg|thumb|right|250px|IgD - B. Catchpole, RVC 2008]]

''Shortened to IgD''.

''Shortened to IgD''.

==Structure==

==Structure==

IgD is Y-shaped. In rodents, it has two heavy chain constant regions, whereas other mammals have three. IgD has a long hinge region and no disulfide bonds.

IgD is Y-shaped. In rodents, it has two δ heavy chain constant regions, whereas other mammals have three. IgD has a long hinge region and no disulfide bonds.

==Function==

==Function==

IgD is only expressed in association with [[IgM]]. It is important in B-cell development.  

IgD is only expressed in association with [[IgM]]. It is thought to be important in B-cell development, although it has been shown in δ chain knockout mice (so they have no functional IgD) do not have any noticeable defects in immune function.

<p> Interestingly IgD serum levels increase in allergic reactions, although it is not known why this is.</p>

==Links==

==Links==

[[Immunoglobulin M|Immunoglobulin M]]

[[Immunoglobulin M|Immunoglobulin M]]

[[Category:Immunoglobulins]]

[[Category:Immunoglobulins]]

[[Category:A&P Done]]

[[Category:A&P Done]]