Changes

Commonly referred to as ''IgE''.

Commonly referred to as ''IgE''.

Unlike [[IgM]], [[IgG]] and [[IgA]], IgE does not function as a soluble antibody, with binding to Fcε receptors before it can bind to the target, and is found in low levels in blood plasma. Like [[IgA]], it is produced by [[B cell differentiation|plasma cells]] and is mainly localised to mucosal surfaces.

Unlike [[IgM]], [[IgG]] and [[IgA]], IgE does not function as a soluble antibody, with binding to Fcε receptors required before it can bind to the target antigen, and is found in low levels in blood plasma. Like [[IgA]], it is produced by [[B cell differentiation|plasma cells]] and is mainly localised to mucosal surfaces.

==Structure==

==Structure==