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*Highly infectious URT disease of cattle  
 
*Highly infectious URT disease of cattle  
 
*Spread by movement of animals, aerosol transmission - requires close contact between animals
 
*Spread by movement of animals, aerosol transmission - requires close contact between animals
*Early stages (only first few days) may show [[Degenerations and Infiltrations - Pathology#Cellular Inclusions|intracellular inclusions]] in the respiratory mucosal epithelial cells
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*Early stages (only first few days) may show [[Cellular Inclusions|intracellular inclusions]] in the respiratory mucosal epithelial cells
 
*Leading to neutrophilic inflammation of varying severity.... serous -> catarrhal -> purulent  
 
*Leading to neutrophilic inflammation of varying severity.... serous -> catarrhal -> purulent  
 
*With secondary bacterial infection (eg: ''[[:Category:Pasteurella and Mannheimia species|Pasturella spp.]], [[:Category:Mycoplasmas|Mycoplasma spp.]], [[Fusobacterium necrophorum]])'' can lead to fibrinous to necrotizing inflammation; mucosal sloughing, ulceration... pyrexia, dyspnoea ... [[Lungs Inflammatory - Pathology#Aspiration pneumonia|inhalation pneumonia]]... death
 
*With secondary bacterial infection (eg: ''[[:Category:Pasteurella and Mannheimia species|Pasturella spp.]], [[:Category:Mycoplasmas|Mycoplasma spp.]], [[Fusobacterium necrophorum]])'' can lead to fibrinous to necrotizing inflammation; mucosal sloughing, ulceration... pyrexia, dyspnoea ... [[Lungs Inflammatory - Pathology#Aspiration pneumonia|inhalation pneumonia]]... death
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