Changes

*organism is widely distributed within the soil and normally present in GIT and [[Liver - Anatomy & Physiology|liver]] of grazing animals on infected pastures

*organism is widely distributed within the soil and normally present in GIT and [[Liver - Anatomy & Physiology|liver]] of grazing animals on infected pastures

**worldwide

**worldwide

*it is ingested by the animal and spores are absorbed via the gut and travel to the [[Liver - Anatomy & Physiology|liver]] , where they lie dormant in [[Macrophages - WikiBlood|macrophages (Kupffer cells)]] - also found in [[Bone Marrow - Anatomy & Physiology|bone marrow]] and [[Spleen - Anatomy & Physiology|spleen]]

*it is ingested by the animal and spores are absorbed via the gut and travel to the [[Liver - Anatomy & Physiology|liver]] , where they lie dormant in [[Macrophages|macrophages (Kupffer cells)]] - also found in [[Bone Marrow - Anatomy & Physiology|bone marrow]] and [[Spleen - Anatomy & Physiology|spleen]]

*seasonal disease associated with Fasciola [[Liver - Anatomy & Physiology|liver]] flukes

*seasonal disease associated with Fasciola [[Liver - Anatomy & Physiology|liver]] flukes

**migrating immature [[Liver - Anatomy & Physiology|liver]] flukes precipitate the disease

**migrating immature [[Liver - Anatomy & Physiology|liver]] flukes precipitate the disease