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− | <big><center>[[Endocrine System - Anatomy & Physiology|'''BACK TO ENDOCRINE SYSTEM ANATOMY & PHYSIOLOGY''']]</center></big>
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− | The [[Urinary System - Anatomy & Physiology#Upper Urinary Tract|Kidney]] synthesises and secretes various products, including [[Endocrine System - Hormones - Anatomy & Physiology|hormones]] and enzymes which have a vital role within the body.
| + | ==Overview== |
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| + | The [[Urinary System Overview - Anatomy & Physiology#Upper Urinary Tract|kidney]] synthesises and secretes various products, including [[Hormones - Anatomy & Physiology|hormones]] and enzymes which have a vital role within the body. |
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− | |<font color=Purple>Renin</font> | + | |'''Renin''' |
− | This enzyme forms a vital part of the [[Renin-Angiotensin-Aldosterone System (RAAS) - Anatomy & Physiology|Renin-Angiotensin-Aldosterone System]], a complex system of hormones and enzymes which act to raise blood pressure when stimulated by hypotension. | + | |This enzyme forms a vital part of theRenin-Angiotensin-Aldosterone System]], a complex system of hormones and enzymes which act to raise blood pressure when stimulated by hypotension. |
− | Renin is the enzyme for the creation of the hormone ''angiotensin''. | + | Renin is the enzyme required for the creation of the hormone ''angiotensin''. |
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− | |<font color=Purple>Erythropoietin</font> | + | |'''[[Erythropoiesis#Regulation|Erythropoietin]]''' |
− | |Erythropoeitin is the vital hormone for [[Erythropoiesis - Anatomy & Physiology|Erythropoeisis]], the production of red blood cells. | + | |Erythropoeitin is the vital hormone for [[Erythropoiesis|erythropoeisis]], the production of red blood cells. |
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− | |<font color=Purple>Calcitriol</font> | + | |'''[[Calcium#Calcitriol (Active Vitamin D3)|Calcitriol]]''' |
− | |Also known as | + | |Also known as ''Active Vitamin D3'', or ''1-25-Dihydroxyvitamin D3'', Calcitriol is vital for [[Calcium|calcium homeostasis]], and acts to raise plasma calcium levels. Within the kidney, vitamin D from dietary sources or the skin is 'activated' by hydroxylation. |
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| + | ==Renin== |
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| + | A proteolytic enzyme synthesised in the kidney. Renin affects blood pressure indirectly and is part of the first stage of the [[Renin Angiotensin Aldosterone System| renin-angiotensin-aldosterone-system]]. Its effects are through its activation of this system by the conversion of angiotensinogen to angiotensin 1. |
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| + | ==Erythropoietin== |
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| + | Erythropoietin is a glycoprotein hormone produced in the kidneys in adult life. Its function is beyond the scope of this section and more information can be found on [[Erythropoiesis#Regulation|regulatioon of erythropoiesis]]. |
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| + | ==Vitamin D== |
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| + | The [[Calcium#Active Vitamin D Synthesis|activation of vitamin D]] is regulated by the kidneys under the influence of another hormone, [[Calcium#Parathyroid Hormone (PTH)|PTH]]. |
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| + | [[Category:Endocrine System - Anatomy & Physiology]][[Category:Kidney - Anatomy & Physiology]] |
| + | [[Category:A&P Done]] |