* Diffuses across the cell membrane - lipophillic (essentially steroidal)
* Diffuses across the cell membrane - lipophillic (essentially steroidal)
−
* Of the principal cells of [[Distal Tubule - Anatomy & Physiology| distal tubule]] and [[Collecting Duct - Anatomy & Physiology| Collecting Duct]]
+
* Of the principal cells of [[Reabsorption and Secretion Along the Distal Tubule and Collecting Duct - Anatomy & Physiology#Distal Tubule| distal tubule]] and [[Reabsorption and Secretion Along the Distal Tubule and Collecting Duct - Anatomy & Physiology#Collecting Duct| collecting duct]]
* Binds to cytoplasmic receptors
* Binds to cytoplasmic receptors
* Works by altering gene transcription and increases synthesis of proteins
* Works by altering gene transcription and increases synthesis of proteins