Changes

==Bile Acids==

==Bile Acids==

Bile acids are composed of cholesterol, bile acids and steroids. The main bile acid is '''cholic acid''' (C24). Conjugated to taurine or glycine in the liver to reduce pKa so they exist in an ionised form as bile salts. Bile salts conjugate with cholesterol and phospholipids and are then secreted into the bile. 95% are recycled in enterohepatic circulation. They emulsify fats which helps absorb fat soluble vitamins. In aqueous solution, they form micelles which are amphiphilic and can transport free fatty acids across the brush border.

Bile acids are composed of cholesterol, bile acids and steroids. The main bile acid is '''cholic acid''' (C24). Conjugated to taurine or glycine in the liver to reduce pKa so they exist in an ionised form as bile salts. Bile salts conjugate with cholesterol and phospholipids and are then secreted into the bile. They emulsify fats which helps absorb fat soluble vitamins. In aqueous solution, they form micelles which are amphiphilic and can transport free fatty acids across the brush border.

 

==Species Differences==

==Species Differences==

[[Image:Canine Liver Topography.jpg|thumb|right|250px|Liver Topography (Dog) - Copyright Nottingham 2008]]

[[Image:Canine Liver Topography.jpg|thumb|right|250px|Liver Topography (Dog) - Copyright Nottingham 2008]]

}}

}}

 

 

[[Category:Liver and Gall Bladder - Anatomy & Physiology]]

[[Category:Liver and Gall Bladder - Anatomy & Physiology]]

[[Category:To Do - AimeeHicks]]

[[Category:To Do - AimeeHicks]]