WikiVet English

Changes

Liver Fibrosis (view source)

Revision as of 19:28, 25 June 2016

313 bytes added ,  19:28, 25 June 2016
no edit summary
Line 1: Line 1:  
== Introduction ==
 
== Introduction ==
−
Any hepatic injury of a moderate degree or more, is going to cause a degree of fibrosis when the lesion has resolved. Fibrosis occurs due to proliferation of the supportive connective tissue in the liver. Fibrosis isolates the [[Liver - Anatomy & Physiology|liver]] cells by effectively changing the sinusoids into capillaries and when a certain amount of fibrosis occurs, it can be self-perpetuating, the end result is a small scarred liver with functional failure.
+
Fibrosis is one way in which the liver responds to injury. It commonly occurs in association with chronic hepatic injury, and represents a repair stage in response to diseases that lead to [[Liver Necrosis|necrosis]] and inflammation. The process is complex and involves increased deposition of extracellular matrix in the liver, following injury-induced activation of [[Hepatic Stellate Cells|stellate cells]].
 +
 +
The distribution pattern of fibrosis is a reflection of the pathogenesis of the condition, and can indicate the type of underlying pathology.
    
==Patterns of Fibrosis ==
 
==Patterns of Fibrosis ==
Line 22: Line 24:     
<big><b>Also see: [[Cirrhosis]]</b></big>
 
<big><b>Also see: [[Cirrhosis]]</b></big>
 +
 +
{{Learning
 +
|Vetstream = [https://www.vetstream.com/canis/search?s=cirrhosis Cirrhosis]<br>[https://www.vetstream.com/canis/Content/Disease/dis01098.asp Idiopathic fibrosis in dogs]
 +
}}
 +
    
== References ==
 
== References ==
Line 35: Line 42:       −
 
+
{{Nicky Parry
 +
|date = 22 August 2011
 +
}}
 
[[Category:Liver_-_General_Pathology]]
 
[[Category:Liver_-_General_Pathology]]
−
[[Category:Nicola Parry reviewing]]
+
[[Category:Nicola Parry reviewed]]
Michuang0720
88

edits

Retrieved from "https://en.wikivet.net/Special:MobileDiff/125179...187349"