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{{review}}
 
{{review}}
 
[[Image:Boa_spleen_crop.jpg|200px|thumb|right|'''Boa constrictor spleen''' (Copyright © RVC)]]
 
[[Image:Boa_spleen_crop.jpg|200px|thumb|right|'''Boa constrictor spleen''' (Copyright © RVC)]]
The immune system of [[Lizard|lizards]] and [[Snake|snakes]] is influenced by age, nutrition, general health, ambient temperature and season (refer to [[Snake Physical Examination|snake physical examination]] and [[Snake Housing|snake housing]]).  In temperate species thymic involution and splenic follicle regression occur seasonally. Antibody production is temperature dependent. The immune system functions most efficiently within a reptile's [[Preferred optimum temperature zone|preferred optimum temperature zone]] although at a low level in comparison to birds and mammals.  In captivity, [[Lizard|lizards]] and [[Snake|snakes]] that are kept below their [[Preferred optimum temperature zone|POTZ]] are immunocompromised and are therefore predisposed to infection with opportunistic pathogens.
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The immune system of [[Lizard|lizards]] and [[Snake|snakes]] is influenced by age, nutrition, general health, ambient temperature and season.  In temperate species thymic involution and splenic follicle regression occur seasonally. Antibody production is temperature dependent. The immune system functions most efficiently within a reptile's [[Preferred optimum temperature zone|preferred optimum temperature zone]] although at a low level in comparison to birds and mammals.  In captivity, [[Lizard|lizards]] and [[Snake|snakes]] that are kept below their [[Preferred optimum temperature zone|POTZ]] are immunocompromised and are therefore predisposed to infection with opportunistic pathogens.
    
'''Find out more about [[:Category:Lizard Diseases|lizard diseases]]'''.
 
'''Find out more about [[:Category:Lizard Diseases|lizard diseases]]'''.
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