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== Introduction  ==

== Introduction  ==

This is a viral disease affecting sheep, grouse, hares, deer, elk, small rodents, ticks and humans; therefore the disease is zoonotic. The reservoir host for this disease is hard ticks (''[[Ixodes ricinus]]'') and this is transmitted to the host by saliva when the tick bites. Therefore, spread mirrors seasonal tick activity.  

This is a viral disease affecting sheep, grouse, hares, deer, elk, small rodents, ticks and humans; therefore the disease is zoonotic. The reservoir host for this disease is hard ticks (''[[Ixodes spp.|Ixodes ricinus]]'') and this is transmitted to the host by saliva when the tick bites. Therefore, spread mirrors seasonal tick activity.  

The virus replicates in [[macrophages]] causing pyrexia and then recovery. The second phase of the virus replication occurs in Purkinje cells of the cerebellum and motor nuclei of the brain stem.

The virus replicates in [[macrophages]] causing pyrexia and then recovery. The second phase of the virus replication occurs in Purkinje cells of the cerebellum and motor nuclei of the brain stem.

== Clinical Signs ==

== Clinical Signs ==

[[Category:Flaviviruses]] [[Category:Sheep_Viruses]] [[Category:Avian_Viruses]] [[Category:Zoonoses]] [[Category:Rodents]] [[Category:Expert_Review - Farm Animal]] [[Category:Neurological_Diseases_-_Sheep]]

[[Category:Flaviviruses]] [[Category:Sheep_Viruses]] [[Category:Avian_Viruses]] [[Category:Zoonoses]] [[Category:Rodents]] [[Category:Expert_Review - Farm Animal]] [[Category:Neurological_Diseases_-_Sheep]]