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*Infection of the joints may result in non-erosive '''arthritis''', causing intermittent bouts of shifting lameness.
*Infection of the joints may result in non-erosive '''arthritis''', causing intermittent bouts of shifting lameness.
*Disease in the heart may cause [[Myocarditis|'''myocarditis''']] with [[Atrio-Ventricular Block|atrio-ventricular block]] and dysrhythmias. This is rare in the UK.
*Disease in the heart may cause [[Myocarditis|'''myocarditis''']] with [[Atrio-Ventricular Block|atrio-ventricular block]] and dysrhythmias. This is rare in the UK.
*'''Lyme Nephritis''' is a form of '''glomerulonephritis''' that may result in acute [[Kidney Renal Failure - Pathology|renal failure]]. This form of renal failure has been described in dogs that were seropositive for ''B. burgdorferi'' sensu stricto in the USA but extensive molecular searches failed to reveal the presence of actual bacteria in the kidneys of affected dogs<ref>Hutton TA, Goldstein RE, Njaa BL, Atwater DZ, Chang YF, Simpson KW. '''Search for Borrelia burgdorferi in kidneys of dogs with suspected "Lyme nephritis".''' ''J Vet Intern Med. 2008 Jul-Aug;22(4):860-5.''</ref>. This form of disease has never been replicated in experimental infections. Associations have been suggested between proteinuria and ''Borrelia'' seroprevalnce, particularly in the Bernese Mountain dog breed. Lyme nephritis, if it is a true phenomenon, occurs much more commonly in the USA than in Europe.
*'''Lyme Nephritis''' is a form of '''glomerulonephritis''' that may result in acute [[:Category:Renal Failure|renal failure]]. This form of renal failure has been described in dogs that were seropositive for ''B. burgdorferi'' sensu stricto in the USA but extensive molecular searches failed to reveal the presence of actual bacteria in the kidneys of affected dogs<ref>Hutton TA, Goldstein RE, Njaa BL, Atwater DZ, Chang YF, Simpson KW. '''Search for Borrelia burgdorferi in kidneys of dogs with suspected "Lyme nephritis".''' ''J Vet Intern Med. 2008 Jul-Aug;22(4):860-5.''</ref>. This form of disease has never been replicated in experimental infections. Associations have been suggested between proteinuria and ''Borrelia'' seroprevalnce, particularly in the Bernese Mountain dog breed. Lyme nephritis, if it is a true phenomenon, occurs much more commonly in the USA than in Europe.
*Presence of organisms in the brain or spinal cord may cause '''neurological signs''' due to meningitis or encephalitis.
*Presence of organisms in the brain or spinal cord may cause '''neurological signs''' due to meningitis or encephalitis.