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*Cause of epizootic pneumonia in cattle known as Shipping Fever, Transit Fever or [[Pneumonic Pasteurellosis|pneumonic pasteurellosis]] (90% caused by ''Mannheimia haemolytica'' Biotype A, serotype 1 but also ''[[Pasteurella multocida]]''
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*Usually secondary to viral infections such as [[Respiratory Viral Infections - Pathology#Parainfluenza- 3|parainfluenza - 3]] or [[Respiratory Viral Infections - Pathology#In Cattle|IBR]], bacterial infections such as ''Mycoplasma'' or environmental stress
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Also known as: '''''Pasteurella haemolytica — M. haemolytica
*May contribute to [[Respiratory Bacterial Infections - Pathology#Enzootic pneumonia of calves|Enzootic pneumonia of calves]]
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*Enzootic pneumonia in sheep
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* [[Peritonitis - Pathology#Peritonitis|Peritonitis in sheep]]
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* [[Oedema - Pathology#Permeability type|Permeability types of pulmonary oedema]]
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*Septicaemia in young lambs
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*Causes gangrenous mastitis in sheep
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*Beta-haemolytic on blood agar
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*Grow weakly on MacConkey agar
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*Odourless
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*All are ''Mannheimia'' A biotypes (previously ''Pasterurella haemolytica'')
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*Strains often produce a cytotoxin, known as leukotoxin, which kills leukocytes of ruminants
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*Leukotoxin is a member of the RTX group toxins, and is probably largely responsible for the pathogenicity of the bacteria in septicaemia and pneumonia
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[[Category:Pasteurella_and_Mannheimia_species]][[Category:Cattle]][[Category:Sheep]]
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==Introduction==
[[Category:To_Do_-_Bacteria]]
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''Mannheimia haemolytica'' is a species of the [[:Category:Pasteurella and Mannheimia species|''Mannheimia'']] genus. It is the cause of epizootic pneumonia in cattle known as Shipping Fever, Transit Fever or [[Pneumonic Pasteurellosis|pneumonic pasteurellosis]]. 90% is caused by ''Mannheimia haemolytica'' Biotype A, serotype 1 but also ''[[Pasteurella multocida]]''. It is usually secondary to viral infections such as [[Bovine Parainfluenza - 3|parainfluenza - 3]] or [[Infectious Bovine Rhinotracheitis|IBR]], bacterial infections such as [[:Category:Mycoplasmas|''Mycoplasma'']] or environmental stress.
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''M. haemolytica'' may contribute to [[Enzootic Pneumonia - Calves|Enzootic pneumonia of calves]]; [[Enzootic Pneumonia - Lambs|Enzootic pneumonia of lambs]] and [[Peritonitis|peritonitis in sheep]]. It also causes gangrenous [[Mastitis|mastitis]] in sheep.
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''M. haemolytica'' is beta-haemolytic on blood agar and grows weakly on MacConkey agar. It is odourless. All are ''Mannheimia'' A biotypes and the strains often produce a cytotoxin, known as leukotoxin, which kills leukocytes of ruminants. Leukotoxin is a member of the RTX group toxins, and is probably largely responsible for the pathogenicity of the bacteria in septicaemia and pneumonia.
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{{Learning
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|literature search = [http://www.cabdirect.org/search.html?rowId=1&options1=AND&q1=%22Mannheimia+haemolytica%22&occuring1=title&rowId=2&options2=OR&q2=%22Pasteurella+haemolytica%22&occuring2=title&rowId=3&options3=AND&q3=&occuring3=freetext&publishedstart=2000&publishedend=yyyy&calendarInput=yyyy-mm-dd&la=any&it=any&show=all&x=60&y=11 ''Mannheimia haemolytica'' publications since 2000]
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{{review}}
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{{OpenPages}}
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[[Category:Pasteurella_and_Mannheimia_species]]
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[[Category:Expert_Review]]
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