Changes

Granulomatous inflammation

Granulomatous inflammation

* ''Mucor'', a fungi, invades the [[The Rumen - Anatomy & Physiology|rumen]] wall, e.g. after damage caused by rumenal acidosis.

* ''Mucor'', a fungi, invades the [[Rumen - Anatomy & Physiology|rumen]] wall, e.g. after damage caused by rumenal acidosis.

* Produces chronic ongoing granulomatous rumenitis.   

* Produces chronic ongoing granulomatous rumenitis.   

* Difficult to diagnose in life.

* Difficult to diagnose in life.

=====Gross=====

=====Gross=====

* Thickening and ulceration of mucosal surface of [[The Rumen - Anatomy & Physiology|rumen]].

* Thickening and ulceration of mucosal surface of [[Rumen - Anatomy & Physiology|rumen]].

** Feels like thick leather.   

** Feels like thick leather.   

*[[The Rumen - Anatomy & Physiology|Rumen]] wall becomes fibrosed.

*[[Rumen - Anatomy & Physiology|Rumen]] wall becomes fibrosed.

=====Histological=====  

=====Histological=====  

* Can visualise fungal hyphae in tissue using special stains (PAS),

* Can visualise fungal hyphae in tissue using special stains (PAS),

** Often grow along blood vessels.

** Often grow along blood vessels.

*** May cause thrombosis of small blood vessels, leading to further necrosis (infarction) of [[The Rumen - Anatomy & Physiology|rumen]] wall.

*** May cause thrombosis of small blood vessels, leading to further necrosis (infarction) of [[Rumen - Anatomy & Physiology|rumen]] wall.