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Transplacental infection results in congenital infection of puppies which is the most typical presentation of the disease. More than one puppy in a litter may be affected, although this may not occur simultaneously. Successive litters can be affected, therefore a dam whelping an infected litter should not be allowed to breed again.  
 
Transplacental infection results in congenital infection of puppies which is the most typical presentation of the disease. More than one puppy in a litter may be affected, although this may not occur simultaneously. Successive litters can be affected, therefore a dam whelping an infected litter should not be allowed to breed again.  
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Other methods of infection include ingestion of sporulated oocysts from dog faecal matter and ingestion of tissue cysts in the tissues of intermediate or incidental hosts, for example bovine placenta.  
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Other methods of infection include ingestion of sporulated oocysts from dog faecal matter and ingestion of tissue cysts in the tissues of intermediate or incidental hosts, for example bovine placenta. The clinical syndrome associated with infection is primarily nueromuscular and is a result of the organism replicating in tissues. Other organ systems may also be affected which may result in pneumonia, ulcerative dermatitis and hepatitis.
 
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==Signalment==
 
==Signalment==
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