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* Marked increase in reproductive activity.
 
* Marked increase in reproductive activity.
 
* Endocrine transition from progesterone to oestrogen dominance under the influence of gonadotrophins LH and FSH.
 
* Endocrine transition from progesterone to oestrogen dominance under the influence of gonadotrophins LH and FSH.
* Follicular growth and regression of the corpus luteum of the previous cycle (in polyoestrous species).
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* Follicular growth and [[Female_Reproductive_Tract_-The_Ovary_-_Anatomy_%26_Physiology#Corpus_Luteum_Regression|regression of the corpus luteum]] of the previous cycle (in polyoestrous species).
 
* Uterus enlarges slightly
 
* Uterus enlarges slightly
 
* Endometrium becomes congested and oedematous, glands show secretory activity.
 
* Endometrium becomes congested and oedematous, glands show secretory activity.
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