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PNS Structure - Anatomy & Physiology (view source)
Revision as of 14:56, 16 August 2009
, 14:56, 16 August 2009no edit summary
* Only capillaries occur within the endoneurial compartment.
* Only capillaries occur within the endoneurial compartment.
** The capillaries of the endoneurium are joined by tight junctions and provide a barrier to large macromolecules.
** The capillaries of the endoneurium are joined by tight junctions and provide a barrier to large macromolecules.
*** This forms the basis of the blood-nerve barrier (BNB), which has similarities to the [[Blood Brain Barrier (BBB)|blood-brain barrier]] of the CNS.
*** This forms the basis of the blood-nerve barrier (BNB), which has similarities to the [[Blood Brain Barrier - Anatomy & Physiology|blood-brain barrier]] of the CNS.
**** The BNB appears to be relatively weak in the sensory ganglia because fenestrations occur between endothelial cells in this location.
**** The BNB appears to be relatively weak in the sensory ganglia because fenestrations occur between endothelial cells in this location.
***** Sensory ganglia are therefore more vulnerable to blood-borne agents.
***** Sensory ganglia are therefore more vulnerable to blood-borne agents.