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==Introduction==
''P.multocida'' is a very small, non-motile, gram-negative, ovoid, coccoid or short rod. It is aerobic and facultatively anaerobic species of the [[:Category:Pasteurella and Mannheimia species|''Pasteurella'']] genus. It forms large, grey colonies on blood agar and is not haemolytic. It does not grow on MacConkey. It has five capsular serotypes, A,B,D,E and F and can be a primary and secondary pathogen. It is responsible for secondary infections following primary viral and mycoplasmal infections, especially in the lungs, for example during [[Enzootic Pneumonia - Calves|Enzootic pneumonia of calves]] and pigs. It can cause [[Haemorrhagic_Disease_Pathophysiology#Vascular_Fragility|vascular fragility]], leading to haemorrhagic disease. It is also involved in [[Bacterial skin infections - Pathology#Subcutaneous abscesses|subcutaneous abscesses]] due to cat bites. It causes [[Pasteurellosis - Rabbit|respiratory disease in rabbits]].
==Type A==
Type A is a commensal in the upper respiratory tract of animals in the UK. It is a primary pathogen in avian cholera - a septicaemia in chickens and turkeys. It is a secondary pathogen commonly responsible for dog and cat bite wound infections in humans and animals. It is also involved in feline pyothorax and cellulitis.
Some strains are involved in [[Atrophic Rhinitis]] of pigs, and produce osteolytic toxin. It is also involved in [[Snuffles|snuffles]] in rabbits, a mucopurulent rhinosinusitis and can cause pneumonia and mastitis in sheep. In cattle it is associated with [[Pneumonic Pasteurellosis|pneumonic pasteurellosis]], as well as enzootic pneumonia in calves.
==Type B==
Type B causes Haemorrhagic Septicaemia of cattle in Southern Europe and Asia.
==Type D==
Type D is a primary and secondary pathogen. It causes [[Atrophic Rhinitis]] along with ''[[Bordetella bronchiseptica]]'' in pigs. ''Pasteurella multocida'' adhere to epithelium damaged by ''[[Bordetella bronchiseptica]]'' and produce an osteolytic toxin (Pmt), which stimulates osteoclasts, inducing bone resorption of the nasal turbinates.
==Type E==
Type E causes African Bovine Haemorrhagic Septicaemia.
{{Learning
[[Category:Cattle]][[Category:Pig]][[Category:Poultry]][[Category:Rabbit]]
|literature search = [http://www.cabdirect.org/search.html?rowId=1&options1=AND&q1=%22Pasteurella+multocida%22&occuring1=title&rowId=2&options2=AND&q2=&occuring2=freetext&rowId=3&options3=AND&q3=&occuring3=freetext&publishedstart=2000&publishedend=yyyy&calendarInput=yyyy-mm-dd&la=any&it=any&show=all&x=50&y=9 ''Pasteurella multocida'' publications since 2000]
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[[Category:Pasteurella and Mannheimia species]].
[[Category:Expert_Review - Bacteria]]