Difference between revisions of "Pasteurella species and Mannheimia haemolytica"

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===Overview ''Pasteurella''===
 
===Overview ''Pasteurella''===
  
*Found in the upper respiratory tract and gastrointestinal tract mucosa  
+
*Common commensal of the upper respiratory tract and gastrointestinal tract mucosa of animals
 
*Usually opportunistic organisms, causing disease during times of stress, low resistance or concurrent infections
 
*Usually opportunistic organisms, causing disease during times of stress, low resistance or concurrent infections
 
*Resist phagocytosis by their capsule
 
*Resist phagocytosis by their capsule
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===Bacteria Properties===
 
===Bacteria Properties===
  
*Short Gram-negative bacilli
+
*Short Gram-negative bacilli or coccobacilli
 
*Oxidase-positive
 
*Oxidase-positive
 
*May show bipolar staining
 
*May show bipolar staining
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===''Pasteurella multocida''===
 
===''Pasteurella multocida''===
 +
 +
*Large grey colonies on blood agar
 +
*Not haemolytic
 +
*Do not grow on MacConkey
 +
*Four capsular serotypes, A,B,D,E and recently F
 +
*Primary and secondary pathogen
 +
*Causes Haemorrhagic Septicaemia in cattle
 +
*Contributes to Atropic Rhinitis in pigs
 +
*Causes septicaemia in chickens and turkeys known as folw cholera
 +
*Involved in Snuffles (Pasteurellosis) in rabbits
 +
*Responsible for secondary infections following primary viral and mycoplasmal infections, especially in the lungs, for example during pig enzootic pneumonia
  
 
*Typa A
 
*Typa A
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*Type D
 
*Type D
**Causes Atropic Rhinitis along with ''Bordetella bronchiseptica''
+
**Causes Atropic Rhinitis along with ''Bordetella bronchiseptica'' in pigs
 
**Produces an osteolytic toxin, which stimulates osteoclast, inducing bone resorption
 
**Produces an osteolytic toxin, which stimulates osteoclast, inducing bone resorption
  

Revision as of 17:25, 16 December 2007

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Overview Pasteurella

  • Common commensal of the upper respiratory tract and gastrointestinal tract mucosa of animals
  • Usually opportunistic organisms, causing disease during times of stress, low resistance or concurrent infections
  • Resist phagocytosis by their capsule
  • Not part of the human bacterial flora

Bacteria Properties

  • Short Gram-negative bacilli or coccobacilli
  • Oxidase-positive
  • May show bipolar staining
  • Catarrhal odour
  • Produce endotoxins which cause host damage and death

Pasteurella multocida

  • Large grey colonies on blood agar
  • Not haemolytic
  • Do not grow on MacConkey
  • Four capsular serotypes, A,B,D,E and recently F
  • Primary and secondary pathogen
  • Causes Haemorrhagic Septicaemia in cattle
  • Contributes to Atropic Rhinitis in pigs
  • Causes septicaemia in chickens and turkeys known as folw cholera
  • Involved in Snuffles (Pasteurellosis) in rabbits
  • Responsible for secondary infections following primary viral and mycoplasmal infections, especially in the lungs, for example during pig enzootic pneumonia
  • Typa A
    • Commensal in upper respiratory tract of animals in UK
    • Commomly repsonsible for dog and cat bite wound infections in humans and animals
    • Some strains involved in Atropic Rhinitis, and produce osteolytic toxin
  • Type B
    • Causes Haemorrhagic Septicaemia of cattle in Southern Europe and Asia
  • Type D
    • Causes Atropic Rhinitis along with Bordetella bronchiseptica in pigs
    • Produces an osteolytic toxin, which stimulates osteoclast, inducing bone resorption
  • Type E
    • Causes Afican Bovine Haemorrhagic Septicaemia

Pasteurella pneumotropica

  • Carried in nasopharynx of many small rodents
  • Causes pneumonia in rodents as a secondary disease