Changes

*Petechial or ecchymotic [[Haemorrhage - Pathology|haemorrhages]] on the skin or mucous membranes.

*Petechial or ecchymotic [[Haemorrhage - Pathology|haemorrhages]] on the skin or mucous membranes.

*[[Haemorrhage - Pathology|Haemorrhages]] from the mucous membranes, producing haematuria, haematochezia, haematemesis, haemoptysis and melaena.

*[[Haemorrhage - Pathology|Haemorrhages]] from the mucous membranes, producing haematuria, haematochezia, haematemesis, haemoptysis and melaena.

*[[Anaemia - Introduction|Anaemia]] with a reactive [[Neutrophilia|neutrophilia]] and [[Monocytosis|monocytosis]] if the haemorrhage is severe.

*[[Regenerative and Non-Regenerative Anaemias|Anaemia]] with a reactive [[Neutrophilia|neutrophilia]] and [[Monocytosis|monocytosis]] if the haemorrhage is severe.

Severe platelet deficiencies may be managed with transfusions of whole blood or, in the USA, with transfusions of platelet cryoprecipitate - this helps to control the anaemia which occurs as a consequence of haemorrhage and which is the life threatening sympton that required correction (rather than the thrombocytopenia).  With both techniques however, it is likely that the transfused platelets have only a short half life in the recipient.   

Severe platelet deficiencies may be managed with transfusions of whole blood or, in the USA, with transfusions of platelet cryoprecipitate - this helps to control the anaemia which occurs as a consequence of haemorrhage and which is the life threatening sympton that required correction (rather than the thrombocytopenia).  With both techniques however, it is likely that the transfused platelets have only a short half life in the recipient.