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Polypeptide Antibiotics
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Revision as of 08:48, 24 October 2008
41 bytes added
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08:48, 24 October 2008
→Spectrum of Activity
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* Action is potentiated by cationic detergents (Chlorohexidine) and by chelating agents (EDTA).
* Action is potentiated by cationic detergents (Chlorohexidine) and by chelating agents (EDTA).
* Have a synergistic action with other antibiotics that are able to penetrate the cell wall of gram negatives.
* Have a synergistic action with other antibiotics that are able to penetrate the cell wall of gram negatives.
−
* Their
actio
is inhibited by the presence of cell debris (pus) and divalent cations.
+
* Their
action
is inhibited by the presence of cell debris (pus) and divalent cations.
−
+
* Able to neutralise bacterial endotoxin.
==Pharmacokinetic Considerations==
==Pharmacokinetic Considerations==
Jtulloch
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