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Potentiated-Sulphonamides (view source)
Revision as of 13:25, 24 October 2008
, 13:25, 24 October 2008→Mechanism of Action
==Mechanism of Action==
==Mechanism of Action==
The combination of sulphonamide and trimethoprim means that the bacterial nucleotide sythesis pathway is attacked at two seperate points. This produces a bactericidal, time-dependent killing affect. To find out how sulphonamides work click [[sulphonamides|here]] and to discover the same about trimethoprim click [[Trimethoprim|here]].
The combination of sulphonamide and trimethoprim means that the bacterial nucleotide sythesis pathway is attacked at two seperate points. This produces a bactericidal, time-dependent killing affect. To find out how sulphonamides work click [[sulphonamides|here]] and to discover the same about trimethoprim click [[Trimethoprim - Dihydrofolate Reductase Inhibitors|here]].
==Spectrum of Activity==
==Spectrum of Activity==