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| ** In dairy cows, up to 2000ml is expelled from the uterus in the first 2-3 days after parturition. | | ** In dairy cows, up to 2000ml is expelled from the uterus in the first 2-3 days after parturition. |
| *** By 14-18 days, locial discharge is almost non-existent in most cows. | | *** By 14-18 days, locial discharge is almost non-existent in most cows. |
| + | |
| + | ==Endometrial Repair== |
| + | === Vasoconstriction === |
| + | * After separation of foetal '''cotyledons''' from maternal '''caruncles''' (within 8-12 hours of delivery of the neonate) vasoconstriction occurs at the base of the maternal caruncle. |
| + | |
| + | === Necrosis === |
| + | |
| + | * Irreversible cell death that leads to sloughing of the caruncular mass leaving necrotic tissue in the lochial fluid inside the [[Uterus - Anatomy & Physiology|uterus]]. |
| + | * Some blood is released from the caruncular stalk generating a blood-tinged fluid. |
| + | |
| + | === Sloughing === |
| + | |
| + | * About 5 days after parturition. |
| + | * Caruncles lose cellular organization and integrity. |
| + | * Chunks of the caruncles detach from the surface. |
| + | * Remnants of blood vessels exposed on the surface. |
| + | |
| + | === Repair === |
| + | |
| + | * After the decidual tissue of the caruncle has sloughed into the uterine lumen, the caruncle begins to undergo repair. |
| + | * Eventually covered again with endometrial epithelium. |
| + | |
| + | |
| + | * At the same time caruncular repair is taking place, the intercaruncular endometrial surfaces undergo repair. |
| + | * Epithelium of the intercaruncular area repairs at a faster rate than the caruncles. |
| + | ** Repair of intercaruncular endometrium is usually complete by day 8 post-partum. |
| + | |
| + | |
| + | * Delay in caruncular repair compared to intercaruncular epithelium is because a large mass of caruncular tissue must undergo necrosis and sloughing before surface epithelial repair can take place. |
| + | |
| + | === Species Differences === |
| + | |
| + | |
| + | * Once again, the most significant example is in the dairy cow. This is the example shown above. However, there are significant species differences. |
| + | |
| + | |
| + | '''''Time Required for Uterine Involution and Resumption of Ovarian Activity in Various Species''''' |
| + | |
| + | {| style="width:75%; height:200px" border="1" |
| + | |
| + | !'''Species''' |
| + | !'''Alpaca''' |
| + | !'''Beef Cow''' |
| + | !'''Bitch''' |
| + | !'''Camel''' |
| + | !'''Dairy Cow''' |
| + | !'''Ewe''' |
| + | !'''Llama''' |
| + | !'''Mare''' |
| + | !'''Queen''' |
| + | !'''Sow''' |
| + | |- |
| + | | '''Time Required for Complete Uterine Involution (days)''' |
| + | | 20 |
| + | | 30 |
| + | | 90 |
| + | | 30-50 |
| + | | 45-50 |
| + | | 30 |
| + | | 20 |
| + | | 21-28 |
| + | | 30 |
| + | | 28-30 |
| + | |- |
| + | | '''Time Required for Resumption of Ovarian Activity''' |
| + | | 5-10 days |
| + | | 50-60 days (inhibited by lactation) |
| + | | 150 days (long natural postpartum anoestrus) |
| + | | 25-40 days or up to 1 year (inhibited by lactation) |
| + | | 18-25 days |
| + | | 180 days (short day breeder) |
| + | | 5-10 days |
| + | | 5-12 days |
| + | | 30 days |
| + | | 7 days (inhibited by lactation) |
| + | |- |
| + | |} |
| + | |
| + | ==Elimination of Bacterial Contamination of the Reproductive Tract== |
| + | Generally, parturition in domestic animals occurs in a non-sterile environment. As a result, bacterial contamination of the reproductive tract, especially the [[Uterus - Anatomy & Physiology|uterus]], is an inevitable sequela to parturition. |
| + | |
| + | * The postpartum tract containing lochia is an ideal environment for the growth of bacteria. |
| + | * Even though myometrial contractions remove the large volume of lochia, bacterial growth can continue. |
| + | * Bacterial contamination is not always associated with pathology. |
| + | * Normal post-partum events eliminate the bacterial flora within a reasonable time. |
| + | * Elevated oestrodiol promotes leukosis in the uterus and elsewhere in the tract. |
| + | |
| + | |
| + | * In some cases, high numbers of bacteria can overwhelm the natural defence mechanisms, resulting in [[Healing and Repair - Pathology#Female|postpartum uterine infection]]. |
| + | * Conditions that predispose the uterus to infection are: |
| + | ** Retained foetal membranes |
| + | ** [[Dystocia]] |
| + | ** Delay in lochial expulsion due to weak myometrial contractions. |
| + | |
| + | ==Factors Influencing the Puerperium== |
| + | |
| + | === Uterine Involution === |
| + | |
| + | ==== Age ==== |
| + | |
| + | * More rapid in primiparia than pleuriparia |
| + | |
| + | ==== Season ==== |
| + | |
| + | * More rapid in spring and summer months. |
| + | |
| + | ==== Suckling vs Milking ==== |
| + | |
| + | * Results are contradictory |
| + | * May be a breed influence on the time taken to return to ovarian cyclicity |
| + | |
| + | ==== Climate ==== |
| + | |
| + | * Heat stress can accelerate and inhibit the speed of involution. |
| + | |
| + | ==== Periparturient Abnormalities ==== |
| + | |
| + | * Dystocia, retained placenta, hypocalcaemia, ketosis, twin calves and metritis delay involution. |
| + | * Periparturient problems cause a delay of the process of involution by ~5-8 days. |
| + | |
| + | ==== Delayed Return to Ovarian Cyclicity ==== |
| + | |
| + | * Inhibits involution |
| + | |
| + | === Restoration of the Endometrium === |
| + | |
| + | * Retained foetal membranes and metritis inhibit healing. |
| + | * Return to ovarian cyclicity may have an influence. |
| + | |
| + | === Return to Ovarian Cyclicity === |
| + | |
| + | This can be affected by; periparturient abnormalities, milk yield, nutrition, breed, parity, season, climate and suckling intensity and milking frequency. |
| + | |
| + | ==Species Differences in the Puerperium== |
| + | |
| + | ===[[Puerperium - Cow|Cow]] === |
| + | |
| + | ===[[Puerperium - Mare|Mare]] === |
| + | |
| + | ===[[Puerperium - Sheep and Goat|Ewe & Nanny Goat]] === |
| + | |
| + | ===[[Puerperium - Sow| Sow]] === |
| + | |
| + | ===[[Puerperium - Bitch| Bitch]]=== |
| + | |
| + | ===[[Puerperium - Cat| Cat ]]=== |
| | | |
| | | |
| [[Category:Pregnancy and Parturition]] | | [[Category:Pregnancy and Parturition]] |
| + | [[Category:Bullet Points]] |