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Predisposed breeds of dog include the Miniature Schnauzer, Cocker Spaniel, Fox Terrier, Chihuahua, Miniature Pinscher, Labrador Retriever, Newfoundland, Mastiff, Boxer, Samoyed and English and French Bulldog.
 
Predisposed breeds of dog include the Miniature Schnauzer, Cocker Spaniel, Fox Terrier, Chihuahua, Miniature Pinscher, Labrador Retriever, Newfoundland, Mastiff, Boxer, Samoyed and English and French Bulldog.
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== Clinical Signs ==
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== History and Clinical Signs ==
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A murmur is usually detected at the initial health check or primary vaccination.
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Exercise intolerance, syncope and signs of [[Heart Failure, Right-Sided|right sided congestive heart failure]] (if severely affected). Sometimes the condition can be asymptomatic if only mildly affected.  
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Clinical signs include exercise intolerance, syncope and signs of [[Heart Failure, Right-Sided|right sided congestive heart failure]] (if severely affected). Animals may be asymptomatic.
    
== Diagnosis ==
 
== Diagnosis ==
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===Physical Examination===
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* Left-sided, systolic murmur with point of maximal intensity over the heart base
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* Grade of murmur correlates with severity of stenosis for fixed obstructions
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* Apex beat may be more palpable on the right hemithorax than the left if severe right ventricular hypertrophy is present.
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History and clinical signs can be indicative of heart disease. Upon physical examination, it is likely that a systolic crescendo-decrescendo ejection murmur over pulmonary artery in the left heart base will be heard. There will usually be normal femoral pulses. There may be signs of right sided congestive heart failure, such as ascites and jugular distension and jugular pulses.
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'''Radiographic''' findings may include right ventricular enlargement (DV view seen at 1 o'clock), right atrial enlargement and pulmonary artery enlargement (DV view seen at 2 o'clock). Changes are seen most clearly on the dorsoventral view.  
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There may be signs of [[Heart Failure, Right-Sided|right sided congestive heart failure]], such as ascites and jugular venous distension and hepatojugular reflux.
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===Thoracic Radiographs===
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Radiographic findings may include right ventricular enlargement (seen at 1 o'clock on a dorsoventral view), right atrial enlargement and pulmonary artery enlargement (seen at 2 o'clock on a dorsoventral view).  
    
'''Echocardiographic''' findings may include right ventricular hypertrophy, poststenotic dilation of the pulmonary artery and abnormal pulmonic valve if the stenotic area is valvular. Doppler can be used to measure the pressure in the stenotic area and visualize abnormal flow.
 
'''Echocardiographic''' findings may include right ventricular hypertrophy, poststenotic dilation of the pulmonary artery and abnormal pulmonic valve if the stenotic area is valvular. Doppler can be used to measure the pressure in the stenotic area and visualize abnormal flow.
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