Changes

The onset of clinical signs in dogs and cats includes behavioral changes, pyrexia, salivation and dilation of pupils.  

The onset of clinical signs in dogs and cats includes behavioral changes, pyrexia, salivation and dilation of pupils.  

Then, the virus will either take the furious form or the dumb form. The '''furious form''' is mostly seen in dogs and cats, however, prior to popular belief, the dumb form is actually the most common form in dogs. Signs of the furious form include abnormal aggression, salivation, and attack without provocation. There may also be disordered wandering, "copulatory" movements, incoordination, convulsions, coma and death within 3-10 days. The '''dumb form''' may or may not follow the furious form, or it may appear alone. This form is most common in ruminants or horses affected with the disease. Signs include [[Bloat|ruminal tympany]], tenesmus, diarrhoea, paralysis of lower jaw, drooling saliva, tremors and progressive paralysis. In dogs, a change in voice may be observed (bellowing).

Then, the virus will either take the furious form or the dumb form. The '''furious form''' is mostly seen in dogs and cats, however, contrary to popular belief, the dumb form is actually the most common form in dogs. Signs of the furious form include abnormal aggression, salivation, and attack without provocation. There may also be disordered wandering, "copulatory" movements, incoordination, convulsions, coma and death within 3-10 days. The '''dumb form''' may or may not follow the furious form, or it may appear alone. This form is most common in ruminants or horses affected with the disease. Signs include [[Bloat|ruminal tympany]], tenesmus, diarrhoea, paralysis of lower jaw, drooling saliva, tremors and progressive paralysis. In dogs, a change in voice may be observed (bellowing).

== Diagnosis  ==

== Diagnosis  ==

For virus-endemic countries, control in pets is achieved by annual vaccination. Antigenicity allows a single antigenic type to vaccinate. The vaccine is either '''inactivated virus''' or '''canarypox''' recombinant viruses. Control is also achieved by control of the stray population, enforcing all dogs to be muzzled in public and attempts to control wildlife hosts by feeding vaccinated bait.

For virus-endemic countries, control in pets is achieved by annual vaccination. Antigenicity allows a single antigenic type to vaccinate. The vaccine is either '''inactivated virus''' or '''canarypox''' recombinant viruses. Control is also achieved by control of the stray population, enforcing all dogs to be muzzled in public and attempts to control wildlife hosts by feeding vaccinated bait.

In humans that may be working with animals and be at risk of contracting the disease then prevention is by vaccination with a single booster if bitten. The current vaccine is grown in human diploid cells (HDCV) and is BPL-inactivated, and is therefore costly. Developing countries utilize older vaccines passaged from a 1939 case ("Flury" vaccines). If bitten and unvaccinated, one should clean and disinfect the wound and human '''anti-rabies immunoglobulin''' should be administered around the bite. Then, an intramuscular vaccination program: 2 dose - 1 dose - 1 dose at 0, 7, and 14 days post-bite should be started.  

In humans that may be working with animals and be at risk of contracting the disease, prevention is by vaccination with a single booster if bitten. The current vaccine is grown in human diploid cells (HDCV) and is BPL-inactivated, and is therefore costly. Developing countries utilize older vaccines passaged from a 1939 case ("Flury" vaccines). If bitten and unvaccinated, one should clean and disinfect the wound and human '''anti-rabies immunoglobulin''' should be administered around the bite. Then, an intramuscular vaccination program: 2 dose - 1 dose - 1 dose at 0, 7, and 14 days post-bite should be started.  

For more on Rabies control in Europe, see [http://www.who-rabies-bulletin.org/About_Rabies/Control.aspx here]

For more on Rabies control in Europe, see [http://www.who-rabies-bulletin.org/About_Rabies/Control.aspx here]