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* The secretion of H⁺ in this section of the nephron is mainly a result of the Na⁺/H⁺ antiporter in the apical membrane using secondary active transport.

* The secretion of H⁺ in this section of the nephron is mainly a result of the Na⁺/H⁺ antiporter in the apical membrane using secondary active transport.

*HCO₃^- is reabsorbed here in a different way to other substances.  The presence of hydrogen in the lumen causes some amount of it to dissociate to carbon dioxide and water via the enzyme carbonic anhydrase.  These enter the epitehlial cells where they are reformed using the same enzyme.  The HCO₃^- then leaves the cell using the basolateral 3HCO₃^-/Na⁺ symporter.

*HCO₃^- is reabsorbed here in a different way to other substances.  The presence of hydrogen in the lumen causes some amount of it to dissociate to carbon dioxide and water via the enzyme carbonic anhydrase.  These enter the epithelial cells where they are reformed using the same enzyme.  The HCO₃^- then leaves the cell using the basolateral 3HCO₃^-/Na⁺ symporter.

*[[Reabsorption and Secretion Along the Proximal Tubule - Anatomy & Physiology#The Secretion of H+ and the Reabsorption of HCO3-|Link to Article]]</TD>

*[[Reabsorption and Secretion Along the Proximal Tubule - Anatomy & Physiology#The Secretion of H+ and the Reabsorption of HCO3-|Link to Article]]</TD>

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