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===Activin===

===Activin===

Activin is a glycoprotein that is produced within granulosa cells in females and sertoli cells in the male. Activin is thought to play an almost directly opposite role to that of inhibin and is involved in many physiological functions including stimulation of FSH synthesis and secretion and other roles including cell proliferation, cell differentiation, apoptosis and homeostasis.

Activin is a glycoprotein that is produced within granulosa cells in females and sertoli cells in the male. Activin is thought to play an almost directly opposite role to that of inhibin and is involved in many physiological functions including stimulation of FSH synthesis and other roles including cell proliferation, cell differentiation, apoptosis and homeostasis.

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In the female activin has an effect on the anterior pituitary gland, specifically on gonadotroph cells resulting in increased FSH secretion. The increased concentrations of activin results in increased FSH binding on the female follicle and FSH-induced aromatisation (increased synthesis of oestrogens). Activin also enhances the action of LH in the ovary.

In the female activin has an effect on the anterior pituitary gland, specifically on gonadotroph cells, resulting in increased FSH secretion. The increased concentrations of activin results in increased FSH binding on the female follicle and FSH-induced aromatisation (increased synthesis of oestrogens). Activin also enhances the action of LH in the ovary.

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