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{{review}}
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{{toplink
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|backcolour = E0EEEE
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|linkpage = Nervous System - Pathology
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|linktext =Nervous System
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|maplink = Nervous System (Content Map) - Pathology
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|pagetype =Pathology
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}}
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<br>
   
==Introduction==
 
==Introduction==
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* Seizures are paroxysmal changes in cerebral cortex electrical activity that start abruptly, end suddenly and have a tendency to recur.
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* '''Seizures''' are paroxysmal changes in cerebral cortex electrical activity that start abruptly, end suddenly and have a tendency to recur.
* Epilepsy is the occurence of recurrent seizures.
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* '''Epilepsy''' is the occurence of recurrent seizures.
    
==Pathophysiology==
 
==Pathophysiology==
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* Generalised seizures may be:
 
* Generalised seizures may be:
 
** Idiopathic
 
** Idiopathic
** Due to an intrinsic disorder in the brain
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** Symptomatic
** Acquired
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*** Due to intracranial disease e.g. neoplasia, storage diseases etc.
*** Due to a lesion in the brain
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** Cryptogenic
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*** There is probably an underlying cause but it cannot be identified by the diagnostic tests available.
 
** Reactive
 
** Reactive
 
*** Due to some extracranial disorder, for example a toxin or metabolic disorder.
 
*** Due to some extracranial disorder, for example a toxin or metabolic disorder.
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#* Consists of transient neurological and behavious changes, which can last from hours to days.
 
#* Consists of transient neurological and behavious changes, which can last from hours to days.
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====Idiopathic Epilepsy====
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====[[Idiopathic Epilepsy]]====
 
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* Idiopathic epilepsy is a relatively common cause of generalised seizures in the dog.
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** NOT in the cat.
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* The onset of seizures is between 1 and 5 years of age.
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* The condition presents as recurrent, unprovoked seizures, with no specific cause.
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* There are no neurological defects between episodes.
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* Seizures tend to start as generalised seizures, with no aura.
      
====Acquired Generalisd Seizures====
 
====Acquired Generalisd Seizures====
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|Lead, organophosphates, metaldehyde, strychnine
 
|Lead, organophosphates, metaldehyde, strychnine
 
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|}
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[[File:Causes of Epilepsy in cats and dogs older than 6 years.pdf|alt=|thumb|Causes of Seizures in Cats and Dogs older than 6 Years]]
    
==Investigation of Seizures==
 
==Investigation of Seizures==
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** Serum lead
 
** Serum lead
 
** MRI and CT scanning, and CSF analysis, help rule out cancer.
 
** MRI and CT scanning, and CSF analysis, help rule out cancer.
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<br><br>
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{{Template:Learning
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|podcasts = [[Seizures podcast|RVC clinical podcast about seizures]]<br>
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}}
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[[Category:Central Nervous System - Pathology]]
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