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− | {{review}}
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− | {{toplink
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− | |backcolour = E0EEEE
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− | |linkpage = Nervous System - Pathology
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− | |linktext =Nervous System
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− | |maplink = Nervous System (Content Map) - Pathology
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− | |pagetype =Pathology
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− | }}
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− | <br>
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| ==Introduction== | | ==Introduction== |
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− | * Seizures are paroxysmal changes in cerebral cortex electrical activity that start abruptly, end suddenly and have a tendency to recur. | + | * '''Seizures''' are paroxysmal changes in cerebral cortex electrical activity that start abruptly, end suddenly and have a tendency to recur. |
− | * Epilepsy is the occurence of recurrent seizures. | + | * '''Epilepsy''' is the occurence of recurrent seizures. |
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| ==Pathophysiology== | | ==Pathophysiology== |
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| * Generalised seizures may be: | | * Generalised seizures may be: |
| ** Idiopathic | | ** Idiopathic |
− | ** Due to an intrinsic disorder in the brain | + | ** Symptomatic |
− | ** Acquired | + | *** Due to intracranial disease e.g. neoplasia, storage diseases etc. |
− | *** Due to a lesion in the brain | + | ** Cryptogenic |
| + | *** There is probably an underlying cause but it cannot be identified by the diagnostic tests available. |
| ** Reactive | | ** Reactive |
| *** Due to some extracranial disorder, for example a toxin or metabolic disorder. | | *** Due to some extracranial disorder, for example a toxin or metabolic disorder. |
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| #* Consists of transient neurological and behavious changes, which can last from hours to days. | | #* Consists of transient neurological and behavious changes, which can last from hours to days. |
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− | ====Idiopathic Epilepsy==== | + | ====[[Idiopathic Epilepsy]]==== |
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− | * Idiopathic epilepsy is a relatively common cause of generalised seizures in the dog.
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− | ** NOT in the cat.
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− | * The onset of seizures is between 1 and 5 years of age.
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− | * The condition presents as recurrent, unprovoked seizures, with no specific cause.
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− | * There are no neurological defects between episodes.
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− | * Seizures tend to start as generalised seizures, with no aura.
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| ====Acquired Generalisd Seizures==== | | ====Acquired Generalisd Seizures==== |
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| |Lead, organophosphates, metaldehyde, strychnine | | |Lead, organophosphates, metaldehyde, strychnine |
| |} | | |} |
| + | [[File:Causes of Epilepsy in cats and dogs older than 6 years.pdf|alt=|thumb|Causes of Seizures in Cats and Dogs older than 6 Years]] |
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| ==Investigation of Seizures== | | ==Investigation of Seizures== |
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| ** Serum lead | | ** Serum lead |
| ** MRI and CT scanning, and CSF analysis, help rule out cancer. | | ** MRI and CT scanning, and CSF analysis, help rule out cancer. |
| + | <br><br> |
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| + | {{Template:Learning |
| + | |podcasts = [[Seizures podcast|RVC clinical podcast about seizures]]<br> |
| + | }} |
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| + | [[Category:Central Nervous System - Pathology]] |