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| + | {{OpenPagesTop}} |
| + | {{Podcasts |
| + | |link = https://bloomsbury.mediacore.tv/podcasts/wikivet-english/infectious-bursal-disease |
| + | }} |
| {{Taxobox | | {{Taxobox |
| |name = Infectious Bursal Disease Virus (IBDV) | | |name = Infectious Bursal Disease Virus (IBDV) |
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| IBDV can '''survive''' in poultry houses for '''122 days''' after removal of infected birds and in contaminated water or feed for 52 days. | | IBDV can '''survive''' in poultry houses for '''122 days''' after removal of infected birds and in contaminated water or feed for 52 days. |
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− | Of the two known serotypes of IBDV, only '''Serotype I''' is pathogenic, causing bursal disease in '''chicks''' by '''selectively''' infecting the cells of the '''[[Bursa of Fabricius]]'''. | + | Of the two known serotypes of IBDV, only '''Serotype 1''' is pathogenic, causing bursal disease in '''chicks''' by '''selectively''' infecting the cells of the '''[[Bursa of Fabricius]]'''. |
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− | This disease is '''notifiable''' to the World Organisation for Animal Health [http://www.oie.int (OIE)]
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| ==Signalment== | | ==Signalment== |
− | IBDV can infect chickens, ducks, geese and guineafowl but only '''chickens''' show clinical signs of disease. | + | IBDV can infect chickens, turkeys, ducks, geese and guineafowl but only '''chickens''' show clinical signs of disease. |
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| Lethal infection is usually seen in chicks '''3-6 weeks old''' due to IBDV being restricted to cells at a certain stage of development. | | Lethal infection is usually seen in chicks '''3-6 weeks old''' due to IBDV being restricted to cells at a certain stage of development. |
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| ===Laboratory Tests=== | | ===Laboratory Tests=== |
− | IBDV antigen can be detected in cloacal bursa or splenic samples by '''Agar Gel Precipitation''' or '''[[Immunofluorescence]]'''. | + | IBDV antigen can be detected in cloacal bursa or splenic samples by '''Agar Gel Precipitation''' or '''[[Immunofluorescence]]'''. RT-PCR is commonly used to detect IBDV. |
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| '''Antibody [[ELISA testing|ELISA]]''' can be used for serological diagnosis within a flock. A mimimum of 30 samples is required. | | '''Antibody [[ELISA testing|ELISA]]''' can be used for serological diagnosis within a flock. A mimimum of 30 samples is required. |
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| '''Hygienic''' measures with appropriate disinfectants are imperative. | | '''Hygienic''' measures with appropriate disinfectants are imperative. |
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− | '''Vaccination''' is also usually required. Both live and inactivated forms are available. Timing is difficult due to interference of maternal immunity, but oil adjuvanted vaccines can extend maternal immunity to 5 weeks. Vaccination can cause immunosuppression and a degree of bursal damage. | + | '''Vaccination''' is also usually required. Both live and inactivated forms are available. Timing is difficult due to interference of maternally-derived antibody, but oil adjuvanted vaccines can extend maternal immunity to 5 weeks. Vaccination can cause immunosuppression and a degree of bursal damage. |
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| ==References== | | ==References== |
− | <references/>
| + | Eterradossi, N. and Saif, Y.M. (2008) '''Infectious Bursal Disease'''. In: '''Diseases of Poultry, 12th Edition''' (eds. Saif, Y.M., Fadly A.M., Glissen J.R., McDougald L.R., Nolan L.K., Swayne D.E.) ''Wiley-Blackwell'', pp 185-208 |
− | Animal Health & Production Compendium, '''Infectious Bursal Disease datasheet''', accessed 05/06/2011 @ http://www.cabi.org/ahpc/
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| + | van den Berg, T. (2007) '''Birnaviridae'''. In: '''Poultry Diseases, 6th Edition''' (eds. Pattison, M., McMullin, P., Bradbury, J., Alexander, D.) ''Saunders, Elsevier'', pp 359-366 |
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| + | {{CABI source |
| + | |datasheet = [http://www.cabi.org/ahpc/?compid=3&dsid=80665&loadmodule=datasheet&page=2144&site=160 infectious bursal disease] and [http://www.cabi.org/ahpc/?compid=3&dsid=79279&loadmodule=datasheet&page=2144&site=160 infectious bursal disease virus] |
| + | |date =5 June 2011 |
| + | }} |
| + | <br><br> |
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− | Animal Health & Production Compendium, '''Infectious Bursal Disease Virus datasheet''', accessed 05/06/2011 @ http://www.cabi.org/ahpc/
| + | {{Dave Cavanagh |
| + | |date = 23 August 2011 |
| + | }} |
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| + | {{OpenPages}} |
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− | {{review}}
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| [[Category:Avian Viruses]] | | [[Category:Avian Viruses]] |
− | [[Category:Viral Organisms]] | + | [[Category:Birnaviridae]] |
| [[Category:Lymphoreticular and Haematopoietic Diseases - Birds]] | | [[Category:Lymphoreticular and Haematopoietic Diseases - Birds]] |
− | [[Category:CABI Expert Review]] | + | [[Category:CABI Expert Review Completed]][[Category:CABI AHPC Pages]] |