Changes

==Introduction==

==Introduction==

Splenic Neoplasms and benign hyperplasia are a consideration once splenomegaly has been detected clinically by palpation or following radiography - some splenic neoplasms are surgically curable.

Splenic Neoplasms and benign hyperplasia are a consideration once splenomegaly has been detected clinically by palpation or following radiography - some splenic neoplasms are surgically curable.

==Haemangiosarcoma==

==Haemangiosarcoma==

[[Haemangiosarcoma|Haemangiosarcomas]] are a highly malignant tumour of vascular endothelial origin (cf [[Haemangioma|Haemangiomas]] which are more benign and generally affect other vascular tissue such as cutaneous vascular tissues). They commonly affect dogs and the most frequently affected areas are the [[Spleen - Anatomy & Physiology|spleen]], [[Heart Structure - Anatomy & Physiology|pericardium, right atrium]], [[Liver - Anatomy & Physiology|liver]] and [[Muscles - Anatomy & Physiology|muscle]].  Cats are less frequently affected; the most common sites for feline haemangiosarcomas are the liver, spleen and [[Peritoneal_Cavity_-_Anatomy_%26_Physiology#Mesenteries|mesentry]]. [[Neoplasia_-_Pathology#Dissemination_of_Malignant_Neoplasia|Metastasis]] occurs via the haematogenous route or via splenic capsule rupture and transabdominal spread.  Metastatic sites include, lungs, liver, omentum and diaphragm. Surgery is the treatment of choice but even with this survival time remains very short.

[[Haemangiosarcoma|Haemangiosarcomas]] are a highly malignant tumour of vascular endothelial origin (cf [[Haemangioma|Haemangiomas]] which are more benign and generally affect other vascular tissue such as cutaneous vascular tissues). They commonly affect dogs and the most frequently affected areas are the [[Spleen - Anatomy & Physiology|spleen]], [[Heart Structure - Anatomy & Physiology|pericardium, right atrium]], [[Liver - Anatomy & Physiology|liver]] and [[Muscles - Anatomy & Physiology|muscle]].  Cats are less frequently affected; the most common sites for feline haemangiosarcomas are the liver, spleen and [[Peritoneal_Cavity_- Anatomy & Physiology#Mesenteries|mesentry]]. [[Neoplasia_-_Pathology#Dissemination_of_Malignant_Neoplasia|Metastasis]] occurs via the haematogenous route or via splenic capsule rupture and transabdominal spread.  Metastatic sites include, lungs, liver, omentum and diaphragm. Surgery is the treatment of choice but even with this survival time remains very short.

==Haematopoietic Neoplasms==

==Haematopoietic Neoplasms==

Systemic mastocytosis (aka systemic mast cell disease) is a myeloproliferative neoplasm of [[Mast Cells|mast cells]] and their precursors. Clinical symptoms are associated with the accumulation of mast cells in different tissues, including bone marrow, skin, the gastrointestinal (GI) tract, the liver and the spleen. It occurs very occasionally in the cat. The spleen can enlarge to liver size in extreme cases.  

Systemic mastocytosis (aka systemic mast cell disease) is a myeloproliferative neoplasm of [[Mast Cells|mast cells]] and their precursors. Clinical symptoms are associated with the accumulation of mast cells in different tissues, including bone marrow, skin, the gastrointestinal (GI) tract, the liver and the spleen. It occurs very occasionally in the cat. The spleen can enlarge to liver size in extreme cases.  

[[Category:Splenic Neoplasia|A]]

[[Category:Splenic Neoplasia|A]]

[[Category:WikiBlood]]

[[Category:WikiBlood]]