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#REDIRECT[[:Category:Subcutaneous Mycoses]]
 
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==Chromoblastomycosis==
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*Occurs in horses, dogs, cats and himans
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*Enters tissue through wounds or sites of tissue trauma
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**Limited to subcutaneous and cutaneous tissues
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*Causes hyperplasia and formation of verrucoid, warty nodules
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**Warts are irregular, vegetative and pedunculated
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*Spread is via the lymphatic system
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**Dissemination to other tissues and organs can occur
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*Chronic condition which will progress if not treated
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*Caused by [[Dermatophytosis|dematiaceous fungi]]:
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**''Exophilia jeanselmeri, Phialophora, Cladosporium carrionii, Fonsecaea pedrosoi''
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*Treatment includes [[Antifungal Drugs#The Azoles|Ketoconazole]], [[Antifungal Drugs#Flucytosine|5-fluorocytosine]] and [[Antifungal Drugs#Polyene Antifungals|amphotericin B]]
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==Chromomycosis==
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*Also called Phaeohyphomycosis
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*Opportunistic
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*Infects horses, dogs and humans
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**Found in wounds and abrasions
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*Caused by [[Dermatophytosis|dematiaceous fungi]]
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**''Dactylaria gallopava, Exophiala pisciphila, E. salmonis, Scolecobasidium humicola, S. tshawytschae, Drechslera, Exophilia jeanselmeri, E. verrucosa, Fonsecaea pelrosoi''
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*Nodular and ulcerating lesions of the skin on the feet, legs and occasionally eyes (in turkeys)
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**Regional granulomatous lymphadenitis
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*Single cells or clusters, spherical and thick-walled
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*Brown pigmented fungal elements
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*Multiply by cross-wall formation or splitting (not budding)
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*Grows on Sabauraud's Dextrose agar ar room temperature
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**Slow growth
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**Takes one month
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*For further information, see [[Dermatophytosis|dematiaceous fungi]]
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==Epizootic Lymphangitis==
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==Eumycotic Mycetoma==
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*''Pseudoallescheria boydii, Curvularia geniculata, Cochliobolus spicifer, Helminthosporium'' spp.
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*Lives in soil
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*Enters the body via wounds
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*Granulomatous abscesses
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*Microcolonies can be seen grossly in exudate or lesions
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**Grains or granules
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**Brown or black embedded in granulation tissue
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**Small, irregularly shaped
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*Infrequent infections of dogs, cats, cattle and horses
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*Usually affect the extremities
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**Can infect the [[Nasal cavity - Anatomy & Physiology|nasal mucosa]]
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***E.g. Bovine nasal granuloma
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**Can also infect the peritoneum and [[Skin - Anatomy & Physiology|skin]]
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*Microscopically:
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**Grains of maduromycosis with wide mycelia (compared to actinomycotic granules)
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**Chlamydospores present
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*Grows on Sabauraud's Dextrose agar
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**Slow
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**Takes 2-3 weeks
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*Treatment includes [[Antifungal Drugs#The Azoles|Ketoconazole]], [[Antifungal Drugs#Flucytosine|5-fluorocytosine]] and [[Antifungal Drugs#Polyene Antifungals|amphotericin B]]
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==Hyphomycosis==
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*Opportunistic infection
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*Rare
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*Caused by ''Penicillium, Beauveria, Acremonium, Fusarium, Paecilomyces''
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*Infects both animals and humans
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==Pythiosis==
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*Causes Mycotic Swamp Fever
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*Also called phycomycosis
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*Occurs in the USA, Australia, New Guinea, India, Brazil, Colombia, Japan, Costa Rica and Indonesia
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*''Pythium insidiosum''
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*Enters via wounds
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**[[Lips - Anatomy & Physiology|Lips]], [[Musculoskeletal System - Anatomy & Physiology#The Head and Neck|head]], [[Musculoskeletal System - Anatomy & Physiology#The Head and Neck|neck]], fetlock, hock and [[Hoof - Anatomy & Physiology|hoof]]
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*Granulomatous infection
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**Necrosis and fistulous tracts
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**Yellow lesions
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*Branching, separated fungi
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*Progressive (rather than systemic) disease
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*Surgery is needed
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==Rhinosporidiosis==
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==Sporotrichosis==
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*''Sporothrix schenckii''
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*Occurs in soil, wood and vegetation
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*Worldwide
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*Exogenous infections through wounds
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*Causes subcutaneous nodules or granulomas
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**Nodules ulcerate discharging pus
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*Spread via the [[Lymphatic System - Anatomy & Physiology|lymphatics]]
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*The [[Bones and Cartilage - Anatomy & Physiology|bones]] and viscera can be involved which terminates in mortality
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**This is rare
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**Reported in dogs and horses
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*Affects dogs, horses, cats, monkeys, mules, camels, donkeys, cattle, fowl and rodents
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**Most commonly seen in horses as an ascending lymphocutaneous infection of the legs
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*Single cell, cigar shaped
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**Usually found within [[Neutrophils - WikiBlood|neutrophils]]
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**Yeast cell clusters with peripheral eosinophilic rays can be seen in tissue sections
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*Stained using PAS, fluorescent antibody and Calcofluor White
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*Latex agglutination and immunodiffusion serology can be performed
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*Grows on Blood agar and Sabouraud's Dextrose agar in one to three weeks
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**At 37°C:
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***Colonies are smooth, cream to tan coloured and soft
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***No mycelium can be seen
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**At 25°C to 27°C:
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***Colonies turn from white and soft to tan to brown to black
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***Leathery, wrinkled and coarse
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***Mycelium can be seen as branching septate hyphae
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***Conidiospores can also be seen
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*Potassium iodide treatment orally
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**[[Antifungal Drugs#Flucytosine|5-fluorocytosine]] and [[Antifungal Drugs#Polyene Antifungals|amphotericin B]] can also be used
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==Further Links==
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*Pathology of [[Mycotic skin infections - Pathology#Subcutaneous mycoses|subcutaneous mycoses]]
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*[[Antifungal Drugs]]
 
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