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#REDIRECT[[:Category:Subcutaneous Mycoses]]
 
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|linkpage =Fungi
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|linktext =FUNGI
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<br>
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[[Chromoblastomycosis]]
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[[Chromomycosis]]
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[[Epizootic Lymphangitis]]
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[[Eumycotic Mycetoma]]
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==Hyphomycosis==
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*''Hyphomyces destruens''
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*Opportunistic infection
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**Associated with trauma
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*Rare
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*Caused by ''Penicillium, Beauveria, Acremonium, Fusarium, Paecilomyces''
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*Infects both animals and humans
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**Mainly affects horses
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*Tropical and semi-tropical countries
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*Progressive disease causing granulating and ulcerating lesions on the legs and lower body
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**Lesions grow rapidly
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**Cause extreme debility
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*Occurs in water
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**Most often seen in ponies with access to ponds
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*Chemotactically attracted to horse hair
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*Does not respond well to treatment
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**Radical surgical excision the best method
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**Experiemental vaccination treatment is currently underway and has shown promising results
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==Pythiosis==
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*Causes Mycotic Swamp Fever
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*Also called phycomycosis
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*Occurs in the USA, Australia, New Guinea, India, Brazil, Colombia, Japan, Costa Rica and Indonesia
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*''Pythium insidiosum''
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*Enters via wounds
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**[[Lips - Anatomy & Physiology|Lips]], [[Musculoskeletal System - Anatomy & Physiology#The Head and Neck|head]], [[Musculoskeletal System - Anatomy & Physiology#The Head and Neck|neck]], fetlock, hock and [[Hoof - Anatomy & Physiology|hoof]]
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*Granulomatous infection
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**Necrosis and fistulous tracts
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**Yellow lesions
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*Branching, separated fungi
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*Progressive (rather than systemic) disease
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*Surgery is needed
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==Rhinosporidiosis==
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*''Rhinosporidium seeberi''
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*Lives in water
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*Causes a chronic, benign disease
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*Affects cattle, mules, horses, dogs and humans
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*Causes polyps on the [[Nasal cavity - Anatomy & Physiology|nasal]] and [[Eye - Anatomy & Physiology|ocular]] mucous membranes
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**Over 90% of cases affecting the [[Nasal cavity - Anatomy & Physiology|nasal]] mucous membranes affects male animals
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*Occurs most frequently in tropical countries
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**Also common in the USA
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*Large sporangia can be seen on wet mounts
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**Endospores visible
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**Sporangia develop into small, globose spores
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*Treatment is by surgical excision
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==Sporotrichosis==
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[[Image:Sporotrichosis horse.jpg|thumb|right|150px|Sporotrichosis in a horse -Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath]]
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[[Image:Sporotrichosis cigar cells.jpg|thumb|right|150px|Sporotrichosis cigar shaped cells -Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath]]
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*''Sporothrix schenckii''
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*Occurs in soil, wood and vegetation
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**Saprophyte of both decaying and healthy vegetation
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*Worldwide
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*Exogenous infections through wounds
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*Sporadic infections
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*Non-contageous
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*Causes subcutaneous nodules or granulomas
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**Nodules ulcerate discharging pus
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*Spread via the [[Lymphatic System - Anatomy & Physiology|lymphatics]]
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*The [[Bones and Cartilage - Anatomy & Physiology|bones]] and viscera can be involved which terminates in mortality
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**This is rare
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**Reported in dogs and horses
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*Affects dogs, horses, cats, monkeys, mules, camels, donkeys, cattle, fowl and rodents
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**Most commonly seen in horses as an ascending lymphocutaneous infection of the legs
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**Can be confused with [[Subcutaneous Mycoses#Epizootic Lymphangitis|epizootic lymphangitis]] in horses
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*Single cell, cigar shaped
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**Usually found within [[Neutrophils - WikiBlood|neutrophils]]
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**Yeast cell clusters with peripheral eosinophilic rays can be seen in tissue sections
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*Stained using PAS, Gram stain (positive), fluorescent antibody and Calcofluor White
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*Latex agglutination and immunodiffusion serology can be performed
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*Grows on Blood agar and Sabouraud's Dextrose agar in one to three weeks
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**At 37°C:
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***Colonies are smooth, cream to tan coloured and soft
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***No mycelium can be seen
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**At 25°C to 27°C:
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***Colonies turn from white and soft to tan to brown to black
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***Leathery, wrinkled and coarse
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***Mycelium can be seen as branching septate hyphae
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***Conidiospores can also be seen
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*Potassium iodide treatment orally
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**[[Antifungal Drugs#Flucytosine|5-fluorocytosine]] and [[Antifungal Drugs#Polyene Antifungals|amphotericin B]] can also be used
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==Further Links==
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*Pathology of [[Mycotic skin infections - Pathology#Subcutaneous mycoses|subcutaneous mycoses]]
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*[[Antifungal Drugs]]
 
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